BDBM26194 4-Hydroxybenzoate, III::4-hydroxybenzoic acid::CHEMBL441343::p-Hydroxybenzoic acid::phenol derivative, 8

SMILES OC(=O)c1ccc(O)cc1

InChI Key InChIKey=FJKROLUGYXJWQN-UHFFFAOYSA-N

Data  31 KI  7 IC50  1 EC50

PDB links: 63 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 26194   

TargetSuccinate-semialdehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against SSADHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kinki University

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by enzyme addition measured after 20 mins by microp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Hiroshima University

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataIC50:  9.35E+3nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Mus musculus)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataIC50:  1.18E+5nMAssay Description:Antagonist activity at TLR2 in mouse RAW264.7 cells assessed as PAM3CSK4-induced NO production measured after 24 hrs by Griess assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Kinki University

LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:α-glucosidase (25 μL, 0.2 U/mL), 25 μL of various concentrations of samples, and 175 μL of 50 mM sodium phosphate buffer (pH 7.0)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against GABATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataIC50:  7.24E+4nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed