BDBM29589 Faridak::LBH-589::LBH-589B::Panobinostat::US10722597, Compound Panobinostat

SMILES Cc1[nH]c2ccccc2c1CCNCc1ccc(\C=C\C(=O)NO)cc1

InChI Key InChIKey=FPOHNWQLNRZRFC-ZHACJKMWSA-N

Data  40 KI  165 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 29589   

TargetHistone deacetylase 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  1nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  80nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  105nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  550nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  4.55E+3nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed