BDBM34651 Amrinon::Amrinone::CHEMBL12856::Cordemcura::INAMRINONE::Inocor::MLS000069829::SMR000058850::Win40680::Wincoram::cid_3698

SMILES Nc1cc(c[nH]c1=O)-c1ccncc1

InChI Key InChIKey=RNLQIBCLLYYYFJ-UHFFFAOYSA-N

Data  4 KI  34 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 34651   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of cyclic GMP sensitive phosphodiesterase PDE 2 of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed