BDBM50139892 (S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propionic acid::(S,S)2-(2-phenyl-1-trimethylammonioethylcarboxamido)propanoate::CHEMBL429950::Phe-Ala

SMILES C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(O)=O

InChI Key InChIKey=MIDZLCFIAINOQN-WPRPVWTQSA-N

Data  3 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139892   

TargetAngiotensin-converting enzyme(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50139892((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propio...)
Affinity DataIC50: >1.00E+6nMAssay Description:50% Inhibitory potency against Angiotensin I converting enzyme from mouse striatum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
University Of Tromsø

Curated by ChEMBL
LigandPNGBDBM50139892((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propio...)
Affinity DataIC50:  180nMAssay Description:Concentration required to inhibit the maximum [14C]-Gly-Sar uptake by human Intestinal peptide transporter PepT1 in Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
University Of Tromsø

Curated by ChEMBL
LigandPNGBDBM50139892((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propio...)
Affinity DataIC50:  7.00E+4nMAssay Description:Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50139892((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propio...)
Affinity DataIC50:  1.00E+3nMAssay Description:50% Inhibitory potency against enkephalinase from mouse striatum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed