BDBM50148827 CHEMBL3769975

SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1cccnc1

InChI Key InChIKey=UEJBOCXPGHSONP-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148827   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148827(CHEMBL3769975)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human SIRT2 using RHKK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148827(CHEMBL3769975)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT1 using RHKK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed