BDBM50239186 1,1-Bis(3''-Indolyl)Methane::3,3''-Diindolylmethane::3,3-Diindolylmethane::Arundine::CHEBI:50182::Diindolylmethane

SMILES C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

InChI Key InChIKey=VFTRKSBEFQDZKX-UHFFFAOYSA-N

Data  5 Kd  17 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50239186   

TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239186(1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...)
Affinity DataEC50:  8.37E+3nMAssay Description:Positive allosteric modulation of Gi coupled human GPR84 expressed in CHO cells assessed as potentiation of decanoic acid-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239186(1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...)
Affinity DataEC50:  2.88E+3nMAssay Description:Positive allosteric modulation of Gi coupled human GPR84 expressed in CHO cells assessed as potentiation of decanoic acid-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239186(1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...)
Affinity DataEC50:  252nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239186(1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by beta-galactosidase complementation assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239186(1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...)
Affinity DataEC50:  6.28E+3nMAssay Description:Positive allosteric modulation of Gi coupled human GPR84 expressed in CHO cells assessed as potentiation of decanoic acid-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50239186(1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...)
Affinity DataEC50:  5.12E+3nMAssay Description:Positive allosteric modulation of Gi coupled human GPR84 expressed in CHO cells assessed as potentiation of decanoic acid-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed