BDBM50258119 CHEMBL495020::N-(2-chloro-4-(2-chloro-N-(cyclopropylmethyl)phenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide

SMILES CC(O)(C(=O)Nc1ccc(cc1Cl)N(CC1CC1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F

InChI Key InChIKey=BFQFDUADWFMIBS-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258119   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258119(CHEMBL495020 | N-(2-chloro-4-(2-chloro-N-(cyclopro...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human LXRbeta expressed in human SH-SY5Y cells co-transfected with Gal4-LBD after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258119(CHEMBL495020 | N-(2-chloro-4-(2-chloro-N-(cyclopro...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human LXRalpha expressed in human SH-SY5Y cells cotransfected with Gal4-LBD after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258119(CHEMBL495020 | N-(2-chloro-4-(2-chloro-N-(cyclopro...)
Affinity DataEC50:  940nMAssay Description:Agonist activity at LXRbeta ligand binding domain (unknown origin) by FRET based SRC1 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50258119(CHEMBL495020 | N-(2-chloro-4-(2-chloro-N-(cyclopro...)
Affinity DataEC50:  1.08E+3nMAssay Description:Agonist activity at LXRalpha ligand binding domain by FRET based SRC1 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed