BDBM50290422 4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide::4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[(4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO]PHENYL}BENZAMIDE::CHEMBL56904
SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cccc(Nc3nccc(n3)-c3cccnc3)c2)CC1
InChI Key InChIKey=JHMBUEWQJDGKGS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50290422
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PKC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Bcr-Abl phosphorylation in BALB/c mouse 3T3 by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of PDGFR phosphorylation in BALB/c mouse 3T3 by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PKA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.75E+5nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair