BDBM92455 CHEMBL265470::STO-609
SMILES OC(=O)c1ccc2c3nc4ccccc4n3c(=O)c3cccc1c23
InChI Key InChIKey=MYKOWOGZBMOVBJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 92455
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCalcium/calmodulin-dependent protein kinase kinase 2 [ P274E](Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 2.42E+4nMpH: 7.5 T: 2°CAssay Description:The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio...More data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 3.18E+4nMAssay Description:Binding affinity at MLCKChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 381nMAssay Description:Inhibition of CaM-KKalphaChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 127nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.18E+4nMAssay Description:Inhibition of ERK2Checked by AuthorMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PIM3 in the presence of 100uM ATPMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 10nMAssay Description:Inhibition of CAMKKbeta in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of PIM2 in the presence of 5uM ATPMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of MNK1 in the presence of 50uM ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of DYRK2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of CAMKKalpha in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: >3.18E+4nMAssay Description:Inhibition of CaM-K4Checked by AuthorMore data for this Ligand-Target Pair