BDBM50366824 Avelox::MOXIFLOXACIN::Moxifl-oxacin

SMILES COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1

InChI Key InChIKey=FABPRXSRWADJSP-MEDUHNTESA-N

Data  1 KI  44 IC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50366824   

TargetDNA gyrase subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50:  2.27E+5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase gyrA S84L mutant supercoiling activity assessed as effect on conversion of relaxed pBR322 DNA to super...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50:  2.75E+4nMAssay Description:Inhibition of Staphylococcus aureus wild-type DNA gyrase supercoiling activity assessed as effect on conversion of relaxed pBR322 DNA to supercoiled ...More data for this Ligand-Target Pair