BDBM50435990 GALETERONE::TOK-001::US9611270, galaterone::VN/124::VN/124-1
SMILES C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CC=C2n1cnc2ccccc12
InChI Key InChIKey=PAFKTGFSEFKSQG-PAASFTFBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50435990
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataEC50: 405nMAssay Description:Displacement of [3H]R1881 from androgen receptor in human PC3 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 670nMAssay Description:Displacement of [3H]R1881 from AR in human LNCaP cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 752nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 845nMAssay Description:Displacement of [3H]R1881 from androgen receptor in human LNCAP cellsMore data for this Ligand-Target Pair