BDBM50454798 7-Benzylidenenaltrexone::BNTX
SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)C\C(=C/c1ccccc1)C2=O)ccc3O
InChI Key InChIKey=WXOUFNFMPVMGFZ-BDQAUFNLSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50454798
Affinity DataKi: 2.80nMAssay Description:Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DPDPE from Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]U-69,593 from human kappa opioid receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]U-69593 from Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Displacement of [3H]U69593 from KOR in guinea pig brain membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair