BDBM50581208 CHEMBL5076535
SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNC(C(=O)OCCN(C)C)c2ccccc2)s1
InChI Key InChIKey=NPCLLJJNGJAEPS-NPHAVVRNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50581208
Affinity DataIC50: 79.4nMAssay Description:Antagonist activity at muscarinic M3 receptor in rat trachea assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Antagonist activity at muscarinic M3 receptor in rat trachea assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair