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Report error Found 2064 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4'
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85027(1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...)
Affinity DataKi:  0.000400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85027(1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...)
Affinity DataKi:  0.000480nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85027(1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...)
Affinity DataKi:  0.000580nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85027(1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...)
Affinity DataKi:  0.000630nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.000870nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.000910nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50483188(CHEMBL1632166)
Affinity DataKi:  0.00145nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM198005(US9221790, 15)
Affinity DataIC50: 0.00200nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM197995(US9221790, 5)
Affinity DataIC50: 0.00500nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 4(Rat)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85026(SB-207266 | N-(1-Butylpiperidine-4-ylmethyl)-1,2-(...)
Affinity DataKi:  0.00560nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.00890nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85026(SB-207266 | N-(1-Butylpiperidine-4-ylmethyl)-1,2-(...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0129nMAssay Description:Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

Target5-hydroxytryptamine receptor 4(Mouse)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKd:  0.0200nMAssay Description:Binding affinity to 5HT4 receptor in guinea pig distal colonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataIC50: 0.0250nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataIC50: 0.0251nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Mouse)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Mouse)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85020(GR-125487 | 5-Fluoro-2-methoxy-1H-indole-3-carboxy...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM197993(US9221790, 3)
Affinity DataIC50: 0.0390nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50399614(CHEMBL2181170)
Affinity DataKi:  0.0398nMAssay Description:Displacement of radioligand from human 5HT4R by Cerep protocol based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0398nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50399614(CHEMBL2181170)
Affinity DataKi:  0.0400nMAssay Description:Displacement of radioligand from human 5HT4R by Cerep protocol based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50483175(CHEMBL1632165)
Affinity DataKi:  0.0427nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50327858(CHEMBL114112 | SB207710 | 8-Amino-7-iodo-2,3-dihyd...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50023377(CHEMBL3329805)
Affinity DataKi:  0.0501nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM85026(SB-207266 | N-(1-Butylpiperidine-4-ylmethyl)-1,2-(...)
Affinity DataKi:  0.0525nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50483174(CHEMBL1632163)
Affinity DataKi:  0.0537nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataKi:  0.0631nMAssay Description:Compound was evaluated for its ability to inhibit the binding of 5-HT4 receptor radioligand [125I]SB 207710 to piglet hippocampal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50483187(CHEMBL1632169)
Affinity DataKi:  0.0646nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM197997(US9221790, 7)
Affinity DataIC50: 0.0670nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 4(Guinea pig)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM82505(CAS_121881 | NSC_121881 | SB204070)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0741nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM198000(US9221790, 10)
Affinity DataIC50: 0.0760nMAssay Description:The binding affinity of the compounds for a human 5-HT4 receptor was assayed according to the method as disclosed in the literature [Wyngaert et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0780nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4D receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.0790nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50327858(CHEMBL114112 | SB207710 | 8-Amino-7-iodo-2,3-dihyd...)
Affinity DataKi:  0.0790nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Cnrs Upr 9023

Curated by PDSP Ki Database
LigandPNGBDBM50398985(CHEMBL2177130)
Affinity DataKi:  0.0794nMAssay Description:Displacement of [3H](1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate from human 5HT4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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