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Report error Found 10 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor [C1156Y]'
TargetALK tyrosine kinase receptor [C1156Y](Human)
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM199945(US9226923, 3)
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human AL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [C1156Y](Human)
Nanjing Allgen Pharma

US Patent
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human AL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 7.67nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM179803(3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...)
Affinity DataIC50: 133nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 651nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM179800(3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...)
Affinity DataIC50: 1.31E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM179798(3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...)
Affinity DataIC50: 1.52E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM179804(3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...)
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM179802(3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...)
Affinity DataIC50: 2.99E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor [C1156Y](Human)
Tianjin University of Science and Technology

LigandPNGBDBM179799(4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...)
Affinity DataIC50: 4.08E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed