Report error Found 2872 Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor'
Affinity DataKd: 0.00000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataKd: 0.00000100nMAssay Description:In vivo inhibition of Beta-1 adrenergic receptor in guinea pig right atria after 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataKd: 0.0000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataKd: 0.0000100nMAssay Description:In vivo inhibition of Beta-1 adrenergic receptor in guinea pig right atria after 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataKd: 0.00100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 40 minMore data for this Ligand-Target Pair
Affinity DataKi: 0.0230nMAssay Description:Displacement of [125I]Iodocyanopindolol from human adrenergic beta1 receptor expressed in insect sf9 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0398nMAssay Description:Agonist activity at beta-1 adrenergic receptor in guinea pig trachea assessed as inhibition of electrical stimulation-induced muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0631nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor S190A mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.0631nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor W134A mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.0631nMAssay Description:Antagonist activity at rat wild type beta-1 adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKd: 0.0794nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor Y356F mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Mouse)
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)
Curated by ChEMBL
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]-CGP-12177 from murine beta1-adrenergic receptor expressed in HEK293T cells after 60 mins by radioligand competition binding assa...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Antagonist activity at human adrenergic beta-1 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Agonistic activity against human Beta-1 adrenergic receptor by measuring cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Agonist activity at Homo sapiens (human) beta1 adrenoreceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Mouse)
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)
Curated by ChEMBL
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-CGP-12177 from murine beta1-adrenergic receptor expressed in HEK293T cells after 60 mins by radioligand competition binding assa...More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of I-iodocyanopindolol binding to human beta 1 adrenergic receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.316nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor Y356A mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.316nMAssay Description:Agonist activity at beta-1 adrenergic receptor in guinea pig trachea assessed as inhibition of electrical stimulation-induced muscle contractionMore data for this Ligand-Target Pair
Affinity DataKd: 0.331nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataKd: 0.331nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Displacement of [3H](-)-CGP-12177 from adrenergic beta1 receptor by cell based assayMore data for this Ligand-Target Pair







































