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Report error Found 12025 Enz. Inhib. hit(s) with Target = 'Cholinesterase'
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241982(CHEMBL4093201)
Affinity DataKd:  7.30E+6nMAssay Description:Binding affinity to human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50574801(CHEMBL4847128)
Affinity DataKd:  350nMAssay Description:Pseudo-irreversible inhibition of equine serum BuChE assessed as binding affinity in an equilibrium state using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50574799(CHEMBL4870785)
Affinity DataKd:  13nMAssay Description:Pseudo-irreversible inhibition of equine serum BuChE assessed as binding affinity in an equilibrium state using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataKd:  1.15E+3nMAssay Description:Pseudo-irreversible inhibition of equine serum BuChE assessed as binding affinity in an equilibrium state using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50599167(CHEMBL5195228)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to human BChE assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50599186(CHEMBL5201089)
Affinity DataKd:  0.0640nMAssay Description:Binding affinity to human BChE assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50624436(CHEMBL5429305)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to human BChE assessed as dissociation constant by Surface Plasmon Resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50634022(CHEMBL2296788)
Affinity DataEC50:  4.13E+4nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50634023(CHEMBL5439936)
Affinity DataEC50:  4.69E+4nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50634024(CHEBI:2942 | AZADIRACTIN)
Affinity DataEC50:  6.81E+4nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50634778(CHEMBL5532599)
Affinity DataKd:  759nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50634788(CHEMBL5558492)
Affinity DataKd:  148nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50634775(CHEMBL5557312)
Affinity DataKd:  62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50433314([14C]-Tacrine Monohydrate Monohydrochloride | CHEM...)
Affinity DataKd:  49nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataKd:  7.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataKoff:  2.40E+3s-1Assay Description:Irreversible inhibition of equine serum BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataKoff:  2.37E+3s-1Assay Description:Irreversible inhibition of equine serum BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataKoff:  2.48E+3s-1Assay Description:Irreversible inhibition of equine serum BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataKoff:  1.30E+5s-1Assay Description:Irreversible inhibition of human plasma BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50235799(CHEMBL4096024)
Affinity DataKoff:  1.00E+5s-1Assay Description:Irreversible inhibition of human plasma BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50235801(CHEMBL4098455)
Affinity DataKoff:  1.22E+5s-1Assay Description:Irreversible inhibition of human plasma BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218506(3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimeth...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218521(3-{3-[(benzylethylamino)-methyl]-phenyl}-6,7-dimet...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218525(6,7-dimethoxy-3-(4-{[(4-methoxybenzyl)methylamino]...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218504(3-{3-[(benzylmethylamino)methyl]phenyl}-6,7-dimeth...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218507(6,7-dimethoxy-3-(4-{[(3-nitrobenzyl)methylamino]me...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218508(6,7-dimethoxy-3-(4-{[(3-methoxybenzyl)methylamino]...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218522(6-amino-3-{4-[(benzylmethylamino)methyl]phenyl}-ch...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218519(6,7-dimethoxy-3-(4-{[(2-nitrobenzyl)methylamino]me...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218511(6,7-dimethoxy-3-(4-{[(4-nitrobenzyl)methylamino]me...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218524(6-[(benzylmethylamino)methyl]-2,3-dimethoxyxanthen...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218529(6,7-dimethoxy-3-(4-{[(4-methylbenzyl)methylamino]m...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218526(6,7-dimethoxy-3-(4-{[(3-methylbenzyl)methylamino]m...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218516(6,7-dimethoxy-3-(4-{[(2-methylbenzyl)methylamino]m...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218523(2-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimeth...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218503(3-{3-[(benzylmethylamino)methyl]phenyl}-7-methoxyc...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218514(2-{4-[(benzylmethylamino)methyl]phenyl}-7-methoxyc...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218510(3-{4-[(benzylmethylamino)methyl]phenyl}-6-nitrochr...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50218509(2-{3-[(benzylmethylamino)methyl]phenyl}-6,7-dimeth...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50599186(CHEMBL5201089)
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of horse serum BChE using acetylthiocholine iodide or butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50349922(CHEMBL1814730)
Affinity DataIC50: 0.0212nMAssay Description:Inhibition of BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 0.0267nMAssay Description:Inhibition of BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM9027(3-(1H-indol-3-yl)-N-(3-{methyl[3-(1,2,3,4-tetrahyd...)
Affinity DataIC50: 0.0300nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50587056(CHEMBL5080685)
Affinity DataIC50: 0.0352nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50349923(CHEMBL1814731)
Affinity DataIC50: 0.0354nMAssay Description:Inhibition of BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50599186(CHEMBL5201089)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human BChE using acetylthiocholine iodide or butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50380553(CHEMBL2019034)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50393864(CHEMBL2158116)
Affinity DataIC50: 0.0447nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride substrate incubated for 5 mins before substrate addition measured at 3 min interva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50349921(CHEMBL1814729)
Affinity DataIC50: 0.0449nMAssay Description:Inhibition of BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50647164(CHEMBL5592238)
Affinity DataIC50: 0.0480nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
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