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Report error Found 341 Enz. Inhib. hit(s) with Target = 'DNA polymerase beta'
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50407496(CHEMBL5284382)
Affinity DataIC50: 5nMAssay Description:Inhibition of human DNA polymerase beta by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50638112(CHEMBL5557939)
Affinity DataIC50: 204nMAssay Description:Inhibition of DNA polymerase beta (unknown origin) measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50293303(gallic acid 5,6-dihydroxy-3-carboxyphenylester | C...)
Affinity DataKi:  390nMAssay Description:Inhibition of DNA polymerase beta from human KB3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50623038(CHEMBL5431041)
Affinity DataIC50: 400nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50253141([(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,...)
Affinity DataKi:  600nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50253100([(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-...)
Affinity DataKi:  900nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50253142([(2R,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50408425(CHEMBL2092835)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50408425(CHEMBL2092835)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50250427((+)-Myristinin D | CHEMBL448072)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in absence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50241922(CHEMBL486991 | sodium ((2S,5R)-5-(4-amino-2-oxopyr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50164648(thymidine 5'-(tetrahydrogen triphosphate) | dTTP |...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human DNA polymerase-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50335554(({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human DNA polymerase beta by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50638112(CHEMBL5557939)
Affinity DataKi:  1.80E+3nMAssay Description:Irreversible inhibition of DNA polymerase beta (unknown origin) assessed as inhibition constant by Kitz-Wilson plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184757((3aR,4R,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50259787(3-trans-p-coumaroyl maslinic acid | CHEMBL453751)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50292441(1beta-hydroxyaleuritolic acid 3-p-hydroxybenzoate ...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50408426(CHEMBL2092833)
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184758((3aS,4S,7R,7aR)-1,6-didodecyl-2,7-bis(methoxycarbo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184756((3aR,4S,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50259782(3beta-hydroxyrus-18,20(30)-dien-28-oic acid | CHEM...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50250426((+)-Myristinin A | CHEMBL465365)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in absence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 mg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50250305(3alpha-O-trans-p-coumaroyl-7-labden-15-oic acid | ...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184755((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(methoxycar...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50259781(3beta-hydroxyrus-12,19(29)-dien-28-oic acid | CHEM...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50079577((4aS,6aS,6bR,10S,12aR,14bS)-10-Hydroxy-2,2,6a,6b,9...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50259787(3-trans-p-coumaroyl maslinic acid | CHEMBL453751)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50250427((+)-Myristinin D | CHEMBL448072)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50184752((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(isopropoxy...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50109030(4-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition constant at a concentration of 5 uM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50250305(3alpha-O-trans-p-coumaroyl-7-labden-15-oic acid | ...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50623035(CHEMBL1977402)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DNA polymerase beta incubated for 30 mins in presence of dNTP by PAGE based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50623036(CHEMBL1985644)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DNA polymerase beta incubated for 30 mins in presence of dNTP by PAGE based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50377969(CHEMBL1162297)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50615505(CHEMBL5290566)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50259781(3beta-hydroxyrus-12,19(29)-dien-28-oic acid | CHEM...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50448689(CHEMBL3127730)
Affinity DataKi:  5.50E+3nMAssay Description:Competitive inhibition of recombinant rat DNA polymerase beta using poly(dA)/oligo(dT)18 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50259782(3beta-hydroxyrus-18,20(30)-dien-28-oic acid | CHEM...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50203241(bisnorstriatol | 1, 3-dihydroxy-5-[14'-(3' ',5' '-...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50241611(1, 3-dihydroxy-5-[14'-(3' ',5' '-dihydroxyphenyl)-...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50027113(2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18...)
Affinity DataIC50: 6.60E+3nMAssay Description:Ability to inhibit mouse beta DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50109030(4-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition constant at a concentration of 5 uM on rat DNA polymerase beta as a function of nucleotide substrate concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50027121(2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18...)
Affinity DataIC50: 7.40E+3nMAssay Description:Ability to inhibit mouse beta DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50250356(protolichesterinic acid | (+)-protolichesterinic a...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50079577((4aS,6aS,6bR,10S,12aR,14bS)-10-Hydroxy-2,2,6a,6b,9...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50241610(1,3-dihydroxy-5-[14'-(3' ',5' '-dihydroxyphenyl)-c...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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