Compile Data Set for Download or QSAR
Report error Found 443 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 6B'
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50652776(CHEMBL4786329)
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM6B (1043 to 1643 residues)(unknown origin) by Alphalisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50652775(CHEMBL4303308)
Affinity DataIC50: 1nMAssay Description:Inhibition of epitope-tagged KDM6B (1026 to 1682 residues)(unknown origin) transfected in human U2OS cells using H3K27me2 peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM195611(GSKJ1)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of epitope-tagged KDM6B (1026 to 1682 residues)(unknown origin) transfected in human U2OS cells using H3K27me2 peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50652776(CHEMBL4786329)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of epitope-tagged KDM6B (1026 to 1682 residues)(unknown origin) transfected in human U2OS cells using H3K27me2 peptide as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM195611(GSKJ1)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of KDM6B (1043 to 1643 residues)(unknown origin) by Alphalisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of epitope-tagged KDM6B (1026 to 1682 residues)(unknown origin) transfected in human U2OS cells using H3K27me2 peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50652775(CHEMBL4303308)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of KDM6B (1043 to 1643 residues)(unknown origin) by Alphalisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of KDM6B (1043 to 1643 residues)(unknown origin) by Alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 16nMAssay Description:Inhibition of C-terminal FLAG-tagged human KDM6B expressed in expressed in Sf9 cells pre-incubated for 4 hrs before substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 28nMAssay Description:Inhibition of KDM6B (unknown origin ) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 60nMAssay Description:Inhibition of JMJD3 (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM195611(GSKJ1)
Affinity DataIC50: 60nMAssay Description:Competitive inhibition of KDM6B (unknown origin) using biotinylated H3K27me3 peptide as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 60nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM195611(GSKJ1)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human N-terminal His6/Flag-tagged TEV-protease cleavage site fused JMJD3 1637-1675 deletion mutant (1141 to 1682 residues) ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 63nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM293686(3-({[7-(furan-3-yl)-3,4-dihydro-2H-1-benzopyran-4-...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM293691(3-({[(4S)-7-(thiophen-3-yl)-3,4-dihydro-2H-1-benzo...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant JMJD3 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 150nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50140574(CHEMBL3753391)
Affinity DataIC50: 150nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 160nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2016
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50140567(CHEMBL3752893)
Affinity DataIC50: 200nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 200nMAssay Description:Inhibition of KDM6B (unknown origin) expressed in Escherichia coli and measured after 1 hrs by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50140345(CHEMBL3752179)
Affinity DataIC50: 210nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50140680(CHEMBL3753740)
Affinity DataIC50: 270nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 316nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50005781(CHEBI:65324 | ALVESPIMYCIN)
Affinity DataIC50: 400nMAssay Description:Inhibition of KDM6B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 400nMAssay Description:Inhibition of KDM6B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 400nMAssay Description:Inhibition of KDM6B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50140678(CHEMBL3752769)
Affinity DataIC50: 490nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM373163(2-{1-[2-(4-fluorophenyl)ethyl]-1H-imidazol- 4-yl}-...)
Affinity DataIC50: 500nMAssay Description:The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM319659(2-{1-[2-(3-fluorophenyl)ethyl]-1H-imidazol-4-yl}-4...)
Affinity DataIC50: 500nMAssay Description:The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM293676(3-({[(4R)-7-[methyl(phenyl)amino]-3,4-dihydro-2H-1...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270503(3-[({(1R)-5-[methyl(4-methylphenyl)amino]iso-indol...)
Affinity DataIC50: 550nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270495(3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270502(3-[({(1S)-5-[methyl(4-methylphenyl)amino]iso-indol...)
Affinity DataIC50: 550nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270494(3-[({(1S)-6-[methyl(4-methylphenyl)amino]-1,2,3,4-...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM293712(3-({[(4S)-7-[(4-fluorophenyl)sulfanyl]-3,4-dihydro...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270506(3-[({(1S)-5-[2-methyl-4-(2,2,2-trifluoroethoxy)phe...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270495(3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM293683(3-{[(2-phenyl-5,6,7,8-tetrahydroquinolin-5- | US10...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270502(3-[({(1S)-5-[methyl(4-methylphenyl)amino]iso-indol...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270494(3-[({(1S)-6-[methyl(4-methylphenyl)amino]-1,2,3,4-...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM293687(3-({[(4S)-7-(3-methylphenyl)-3,4-dihydro-2H-1-benz...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270499(3-{[((1R)-6-{methyl[4-(methylethyl)phenyl]amino}-1...)
Affinity DataIC50: 550nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270499(3-{[((1R)-6-{methyl[4-(methylethyl)phenyl]amino}-1...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM270498(3-{[((1S)-6-{methyl[4-(methylethyl)phenyl]amino}-1...)
Affinity DataIC50: 550nMAssay Description:JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50140576(CHEMBL3752835)
Affinity DataIC50: 550nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM293694(3-({[(4S)-7-(2-methylthiophen-3-yl)-3,4-dihydro-2H...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

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