Compile Data Set for Download or QSAR
Report error Found 366 Enz. Inhib. hit(s) with Target = 'Nucleoprotein'
TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614640(US20230270751, Example 200 | (5R)-2-[4-(Dimethyls...)
Affinity DataEC50:  1nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein TPR(Mouse)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TPR-MET in mouse BAF3 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM50256886(CHEMBL4091425)
Affinity DataIC50: 2nMAssay Description:Inhibition of Respiratory syncytial virus A2 protein N by luciferase reporter-based RSV minigenome assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601556(2-(2,4- Difluorophenyl)-6- methyl-N-[(3S)-2- oxo-5...)
Affinity DataEC50:  8nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614454(US20230270751, Example 31 | (5S)-N-[(3S)-9- fluoro...)
Affinity DataEC50:  11nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601514(2-[6-(Cyclopropylamino)-2-fluoropyridin-3-yl]-N-[(...)
Affinity DataEC50:  13nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601532(2-[6- (Ethylamino)-2- fluoropyridin-3- yl]-N-[(3S)...)
Affinity DataEC50:  13nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50652248(NUCLEOZIN)
Affinity DataKd:  14nMAssay Description:Binding affinity to influenza A virus Nucleoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614566(US20230270751, Example 137 | (5R)-2-(2-Fluoro-4- m...)
Affinity DataEC50:  15nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614477(US20230270751, Example 54 | (5R)-2-(4-Ethyl-2- flu...)
Affinity DataEC50:  15nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614564(US20230270751, Example 135 | 2-(2-Fluoro-4- methyl...)
Affinity DataEC50:  15nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614453(US20230270751, Example 30 | (5R)-N-[(3S)-9- fluoro...)
Affinity DataEC50:  16nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601557(2-(2,4- Difluorophenyl)-N- [(3S)-9-fluoro-2-oxo- 5...)
Affinity DataEC50:  17nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601531(2-[6- (Ethylamino)-2- fluoropyridin-3- yl]-N-[(3S)...)
Affinity DataEC50:  18nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601476(2-[2-Fluoro-4- (methylamino)phe- nyl]-N-[(3S)-2-ox...)
Affinity DataEC50:  18nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614633(US20230270751, Example 193 | 2-(2-Fluoro-4-methyls...)
Affinity DataEC50:  19nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614490(US20230270751, Example 67 | (5R)-N-[(3S)-9-fluoro-...)
Affinity DataEC50:  19nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601535(2-[2-Fluoro-6- (propan-2- ylamino)pyridin- 3-yl]-N...)
Affinity DataEC50:  19nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601555(2-(2,4- Difluorophenyl)-N- [(3S)-9-fluoro-2-oxo- 5...)
Affinity DataEC50:  19nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614426(US20230270751, Example 3 | 2-[6-(Ethylamino)-2- fl...)
Affinity DataEC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614570(US20230270751, Example 141 | (5R)-2-(2-Fluoro-4- m...)
Affinity DataEC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614513(US20230270751, Example 90 | (5R)-2-[2-Fluoro-6-[(1...)
Affinity DataEC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601554(2-(2,4- Difluorophenyl)-N- [(3S)-2-oxo-5- phenyl-1...)
Affinity DataEC50:  20nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614450(US20230270751, Example 27 | (5S)-N-[(3S)-9- fluoro...)
Affinity DataEC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601484(N-[(3S)-9- Fluoro-2-oxo-5- phenyl-1,3- dihydro-1,4...)
Affinity DataEC50:  21nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614423(US20230270751, Example 2 | 2-(2,4-Difluorophenyl)-...)
Affinity DataEC50:  22nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601500(N-[(3S)-9- Fluoro-2-oxo-5- phenyl-1,3- dihydro-1,4...)
Affinity DataEC50:  23nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614433(US20230270751, Example 10 | (6R)-N-[(3S)-9- fluoro...)
Affinity DataEC50:  23nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601536(N-[(3S)-9-Fluoro- 2-oxo-5-phenyl- 1,3-dihydro-1,4-...)
Affinity DataEC50:  23nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614448(US20230270751, Example 25 | (5R)-N-[(3S)-9- fluoro...)
Affinity DataEC50:  24nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601527(2-[2-Methyl-6- (propan-2- ylamino)pyridin- 3-yl]-N...)
Affinity DataEC50:  25nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614636(US20230270751, Example 196 | 2-(2,6-Difluorophenyl...)
Affinity DataEC50:  25nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601545(N-[(3S)-9-Fluoro-2-oxo- 5-phenyl-1,3-dihydro- 1,4-...)
Affinity DataEC50:  26nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601504(N-[(3S)-9- Fluoro-2-oxo-5- phenyl-1,3- dihydro-1,4...)
Affinity DataEC50:  27nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601584(6-Chloro-2-(6-ethylpyridin-3-yl)-N-[(3S)-9-fluoro-...)
Affinity DataEC50:  27nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601502(2-(2,4- Difluorophenyl)- N-[(3S)-9- fluoro-2-oxo-5...)
Affinity DataEC50:  27nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601540(N-[(3S)-9-Fluoro- 2-oxo-5-phenyl- 1,3-dihydro-1,4-...)
Affinity DataEC50:  28nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601478(N-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-be...)
Affinity DataEC50:  28nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614475(US20230270751, Example 52 | (5R)-2-[6- (Ethylamino...)
Affinity DataEC50:  28nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614436(US20230270751, Example 13 | 6-Cyclopropyl-N- [(3S)...)
Affinity DataEC50:  28nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601586(N-[(3S)-9-fluoro- 2-oxo-5-phenyl- 1,3-dihydro-1,4-...)
Affinity DataEC50:  28nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601499(2-(2- Fluorophenyl)-6- methyl-N-[(3S)- 2-oxo-5-phe...)
Affinity DataEC50:  29nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614427(US20230270751, Example 4 | N-[(3S)-9-Fluoro-2-oxo-...)
Affinity DataEC50:  29nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614464(US20230270751, Example 41 | N-[(3S)-9-fluoro-2- ox...)
Affinity DataEC50:  29nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601501(2-(2,4- Difluorophenyl)- 5-methyl-N- [(3S)-2-oxo-5...)
Affinity DataEC50:  29nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601570(6-Methyl-2-(6- morpholin-4- ylpyridin-3-yl)-N- [(3...)
Affinity DataEC50:  29nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614438(US20230270751, Example 15 | 2-[6-(Cyclopropylamino...)
Affinity DataEC50:  30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614432(US20230270751, Example 9 | (6S)-N-[(3S)-9- fluoro-...)
Affinity DataEC50:  30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM614505(US20230270751, Example 82 | (5R)-2-(2,4- Difluorop...)
Affinity DataEC50:  31nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Reviral

US Patent
LigandPNGBDBM601479(N-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-be...)
Affinity DataEC50:  31nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

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