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Report error Found 2832 Enz. Inhib. hit(s) with Target = 'Plasminogen'
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518241(CHEMBL4569923)
Affinity DataKi:  0.0410nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518240(CHEMBL4439523)
Affinity DataKi:  0.0510nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532387(CHEMBL4476141)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532387(CHEMBL4476141)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532389(CHEMBL4458743)
Affinity DataKi:  0.130nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532389(CHEMBL4458743)
Affinity DataKi:  0.130nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518249(CHEMBL4588827)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532389(CHEMBL4458743)
Affinity DataKi:  0.150nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532389(CHEMBL4458743)
Affinity DataKi:  0.150nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50425648(CHEMBL2315243)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human plasmin protease domain using Tos-Gly-Pro-Lys-pNA as substrate by micro plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518247(CHEMBL4454304)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50120225(2-{[2-(4-Guanidino-butyrylamino)-3-(4-nitro-phenyl...)
Affinity DataIC50: 0.230nMAssay Description:Concentration required to inhibit Plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108110(US8598206, Table 6, 19)
Affinity DataKi:  0.25nMAssay Description:Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108110(US8598206, Table 6, 19)
Affinity DataKi:  0.25nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532398(CHEMBL4454130)
Affinity DataKi:  0.320nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532398(CHEMBL4454130)
Affinity DataKi:  0.320nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50514073(CHEMBL4576519)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50514062(CHEMBL4436082)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50514076(CHEMBL4456691)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108117(US8598206, Table 6, 2)
Affinity DataKi:  0.400nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50514063(CHEMBL4447001)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532398(CHEMBL4454130)
Affinity DataKi:  0.420nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532398(CHEMBL4454130)
Affinity DataKi:  0.420nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532394(CHEMBL4553652)
Affinity DataKi:  0.430nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532394(CHEMBL4553652)
Affinity DataKi:  0.430nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518253(CHEMBL4579797)
Affinity DataKi:  0.450nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532391(CHEMBL4591922)
Affinity DataKi:  0.450nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532391(CHEMBL4591922)
Affinity DataKi:  0.450nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50514082(CHEMBL4462811)
Affinity DataKi:  0.480nMAssay Description:Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrate after 10 mins by UV/Vis photometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532383(CHEMBL4571212)
Affinity DataKi:  0.510nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532383(CHEMBL4571212)
Affinity DataKi:  0.510nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532394(CHEMBL4553652)
Affinity DataKi:  0.520nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50425654(CHEMBL2315236)
Affinity DataKi:  0.520nMAssay Description:Inhibition of human plasmin protease domain using Tos-Gly-Pro-Lys-pNA as substrate by micro plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532394(CHEMBL4553652)
Affinity DataKi:  0.520nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532384(CHEMBL4560508)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532384(CHEMBL4560508)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to human plasmin assessed as slow binding constant in presence of Mes-DArg-Phe-Arg-AMC after 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM141387(US8921319, 3)
Affinity DataKi:  0.550nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent

TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532384(CHEMBL4560508)
Affinity DataKi:  0.560nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50532384(CHEMBL4560508)
Affinity DataKi:  0.560nMAssay Description:Inhibition of human plasmin using Mes-DSer(Bzl)-Phe-Arg-AMC as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50425656(CHEMBL2315246)
Affinity DataKi:  0.570nMAssay Description:Inhibition of human plasmin protease domain using Tos-Gly-Pro-Lys-pNA as substrate by micro plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108109(US8598206, 122 | US8598206, 118)
Affinity DataKi:  0.600nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108098(US8598206, Table 6, 7)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108098(US8598206, Table 6, 7)
Affinity DataKi:  0.600nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108109(US8598206, 122 | US8598206, 118)
Affinity DataKi:  0.600nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM108106(US8598206, Table 6, 15)
Affinity DataKi:  0.600nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518252(CHEMBL4592533)
Affinity DataKi:  0.610nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518243(CHEMBL4435567)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50518255(CHEMBL4443353)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50425649(CHEMBL2315239)
Affinity DataKi:  0.680nMAssay Description:Inhibition of human plasmin protease domain using Tos-Gly-Pro-Lys-pNA as substrate by micro plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlasminogen(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM141391(US8921319, 15)
Affinity DataKi:  0.680nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent

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