TargetCarbonic anhydrase 9(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 assessed as reduction in CO2 hydration preincubated for 10 mins by stopped flow assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.134nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate after 15 mins by amplex red reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 19.6nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate after 15 mins by amplex red reagent based assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Nottingham
Curated by ChEMBL
University Of Nottingham
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using p-NPP as substrate incubated for 10 mins prior to substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 110nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of calf lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV sp...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 120nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 160nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 200nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 210nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human COX1 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by TLCMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 293nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of calf lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV sp...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 310nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 330nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of calf lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV sp...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 340nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member A1(Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 459nMpH: 6.2Assay Description:The assay results were obtained at 340 nm and ALR1 inhibitory activity was measured with the absorbance change at this respective wavelength. Each we...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 459nMAssay Description:Inhibition of bovine kidney ALR1 using D-glucoronic acid as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University of Science and Technology
Curated by ChEMBL
Abbottabad University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 510nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
Affinity DataIC50: 585nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 740nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...More data for this Ligand-Target Pair
Affinity DataIC50: 781nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Quaid-I-Azam University
Curated by ChEMBL
Quaid-I-Azam University
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using p-nitrophenyl phosphate as substrate preincubated for 10 mins before substrate addition afte...More data for this Ligand-Target Pair
Affinity DataIC50: 930nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Nottingham
Curated by ChEMBL
University Of Nottingham
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 990nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member A1(Bos taurus (Cattle))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 1.08E+3nMpH: 6.2Assay Description:The assay results were obtained at 340 nm and ALR1 inhibitory activity was measured with the absorbance change at this respective wavelength. Each we...More data for this Ligand-Target Pair