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Found 218 with Last Name = 'gunn' and Initial = 'bp'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082933(CHEMBL323720 | [6-(4-Carbamimidoyl-benzoylamino)-c...)
Affinity DataIC50:  2nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082930(CHEMBL117662 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  2nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of fibrinogen binding to purified Human alphaIIb-beta3 integrin in ELISA with 1% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082932(CHEMBL147258 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  5nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082931(CHEMBL148205 | [6-(4-Carbamimidoyl-benzoylamino)-3...)
Affinity DataIC50:  5nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290317(4-{1-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290324(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290319(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  8nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290325(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290325(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082927(CHEMBL344117 | [6-(4-Carbamimidoyl-benzyloxy)-1-ox...)
Affinity DataIC50:  27nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082928(CHEMBL439620 | [6-(4-Carbamimidoyl-benzyloxy)-3,4-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082926(CHEMBL144408 | [6-(4-Carbamimidoyl-benzyloxy)-chro...)
Affinity DataIC50:  39nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290316(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290325(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290321(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290321(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290320(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  46nMAssay Description:Inhibition of fibrinogen binding to purified Human alphaIIb-beta3 integrin in ELISA with 4.5% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290326(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  47nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290323(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  56nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015087(2',4',6'-Trimethyl-biphenyl-4-carboxylic acid hydr...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290315(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  61nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290315(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  61nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290315(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  73nMAssay Description:Inhibition of fibrinogen binding to purified Human alphaIIb-beta3 integrin in ELISA with 4.5% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290321(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  80nMAssay Description:Inhibition of fibrinogen binding to purified Human alphaIIb-beta3 integrin in ELISA with 0.1% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290322(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290315(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  100nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290328(CHEMBL87318 | [(5S,8S,14S,22R,24aS)-22-Carbamoyl-1...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290328(CHEMBL87318 | [(5S,8S,14S,22R,24aS)-22-Carbamoyl-1...)
Affinity DataIC50:  100nMAssay Description:Inhibition of fibrinogen binding to purified Human alphaIIb-beta3 integrin in ELISA with 1% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015178((E)-N-hydroxy-N-methyl-3-(naphthalen-2-yl)acrylami...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  100nMAssay Description:Compound was tested in vitro for inhibition of 12-LO human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290325(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022701(CHEMBL58810 | N-[1-(4-Benzylsulfanyl-phenyl)-ethyl...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibition of 5-lipoxygenase from RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290324(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053509(1-(3-Benzyloxy-phenyl)-[1,2,4]triazinan-3-one | CH...)
Affinity DataIC50:  200nMAssay Description:In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290317(4-{1-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihy...)
Affinity DataIC50:  220nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015163(CHEMBL65655 | N-Hydroxy-N-methyl-3-(2',4',6'-trime...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290326(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  230nMAssay Description:Inhibition of fibrinogen binding to purified Human alphaIIb-beta3 integrin in ELISA with 0.1% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50082937(CHEMBL356574 | [6-(4-Carbamimidoyl-benzyloxy)-1,2,...)
Affinity DataIC50:  260nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290319(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  260nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015159(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-propiona...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015159(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-propiona...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012887(CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022687(CHEMBL61360 | N-Hydroxy-N-[1-(4-styryl-phenyl)-eth...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of 5-lipoxygenase from RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015174(2',4',6'-Trimethyl-biphenyl-4-carboxylic acid hydr...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290320(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  300nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  300nMAssay Description:In vitro 5-lipoxygenase inhibitory activity of the compound against calcium ionophore (A23187) induced LTB4 formation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50290321(3-[6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50:  310nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In DepthDetails Article
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