Compile Data Set for Download or QSAR
maximum 50k data
Found 50 with Last Name = 'comer' and Initial = 'd'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15773((2S)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15774((2R)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15776(2-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15775(1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15772(4-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15756(3-(4-Fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Affinity DataIC50:  6.5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15764(3-(4-Fluorophenyl)-1-methoxy-ethyl-2-pyridin-4-yl-...)
Affinity DataIC50:  21nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15765(3-(4-Fluorophenyl)-1-ethyl-2-pyridin-4-yl-1H-pyrro...)
Affinity DataIC50:  24nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15759(4,7 Diazaindole 22 | 4-[7-(4-fluorophenyl)-5H-pyrr...)
Affinity DataIC50:  53nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15763(3-(4-Fluoro-phenyl)-1-methoxy-2-pyridin-4-yl-1H-py...)
Affinity DataIC50:  68nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15762(3-(4-Fluorophenyl-2-(pyridin-4yl)furo[3,2-b]pyridi...)
Affinity DataIC50:  86nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15766(3-(4-Fluorophenyl)-1-methyl-2-pyridin-4-yl-1H-pyrr...)
Affinity DataIC50:  98nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15767(1-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[...)
Affinity DataIC50:  172nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15768(3-(4-Fluorophenyl)-1-morpholinoethyl-2-pyridin-4-y...)
Affinity DataIC50:  185nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15769(3-(4-Fluorophenyl)-1-pyrrolidinoethyl-2-pyridin-4-...)
Affinity DataIC50:  217nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153917(3-{1-Hydroxy-3-[4-(4-methanesulfonyl-benzyl)-[1,4]...)
Affinity DataIC50:  710nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15760(4,6 Diazaindole 24 | 4-[7-(4-fluorophenyl)-5H-pyrr...)
Affinity DataIC50:  895nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153922(3-{1-(4-Chloro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153910(1,1-di(3-hydroxyphenyl)-3-[4-(4-methylsulfonylbenz...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cell; not determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153927(3-{1-(4-Fluoro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153933(4-{4-[3-Hydroxy-3-(3-hydroxy-phenyl)-3-phenyl-prop...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15758(3-(4-Fluorophenyl)-2-pyridin-4-yl-1H-indole | 3-(4...)
Affinity DataIC50:  1.80E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15770(3-(4-Fluorophenyl)-1-piperidinoethyl-2-pyridin-4-y...)
Affinity DataIC50:  1.97E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153920(3-{1-(3-Fluoro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50:  2.40E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15757(3-(4-Fluorophenyl)-2-pyridin-4-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50:  3.10E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15761(7-(4-Fluoro-phenyl)-6-pyridin-4-yl-7H-pyrrolo[2,3-...)
Affinity DataIC50:  3.30E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153912(1-(3-Hydroxymethyl-phenyl)-3-[4-(4-methanesulfonyl...)
Affinity DataIC50:  4.00E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153919(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50:  4.10E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153925(1-(3-Amino-phenyl)-3-[4-(4-methanesulfonyl-benzyl)...)
Affinity DataIC50:  4.20E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153934(3-{1-(3-Chloro-phenyl)-1-hydroxy-3-[4-(4-methanesu...)
Affinity DataIC50:  4.50E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153913(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153937(4-Methyl-thiophene-2-carboxylic acid N''-(2-{4-[3-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153935(1,1-Bis-(4-fluoro-phenyl)-3-[4-(4-methanesulfonyl-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153926(4-Methyl-thiophene-2-carboxylic acid N''-{2-[4-(4-...)
Affinity DataIC50:  7.40E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153936(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50:  7.90E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153924(3-{1-(3,5-Difluoro-phenyl)-1-hydroxy-3-[4-(4-metha...)
Affinity DataIC50:  9.30E+3nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153915(1,1-Bis-(4-chloro-phenyl)-3-[4-(4-methanesulfonyl-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153911(1-(3,3-Diphenyl-propyl)-4-pyridin-4-ylmethyl-[1,4]...)
Affinity DataIC50:  1.10E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153916(1-(3-Fluoro-phenyl)-3-[4-(4-methanesulfonyl-benzyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153931(1-(3,3-Diphenyl-propyl)-4-(4-methanesulfonyl-benzy...)
Affinity DataIC50:  1.30E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153928(3-[4-(4-Methanesulfonyl-benzyl)-[1,4]diazepan-1-yl...)
Affinity DataIC50:  1.60E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153930(1-(3,3-Diphenyl-propyl)-4-(4-nitro-benzyl)-[1,4]di...)
Affinity DataIC50:  1.90E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153923(1,1-di(4-hydroxyphenyl)-3-[4-(4-methylsulfonylbenz...)
Affinity DataIC50:  2.10E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

LigandPNGBDBM15771(2-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[...)
Affinity DataIC50:  2.36E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153918(CHEMBL362889 | Thiophene-2-carboxylic acid N''-(2-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153932(CHEMBL185282 | Thiophene-2-carboxylic acid N''-{2-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153909(1,1-Bis-(3-fluoro-phenyl)-3-[4-(4-methanesulfonyl-...)
Affinity DataIC50:  3.40E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153921(4-[4-(3,3-Diphenyl-propyl)-[1,4]diazepan-1-ylmethy...)
Affinity DataIC50:  4.30E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153929(1,1-Bis-(4-dimethylamino-phenyl)-3-[4-(4-methanesu...)
Affinity DataIC50:  4.50E+4nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50153914(1-(4-Chloro-benzyl)-4-(4-methanesulfonyl-benzyl)-[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed