Affinity DataKi: 236nMAssay Description:Inhibition of human thymidine phosphorylase by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+3nMAssay Description:Inhibition of human thymidine phosphorylase by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.03E+3nMAssay Description:Inhibition of human thymidine phosphorylase by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.34E+4nMAssay Description:Inhibition of human thymidine phosphorylase by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.35E+4nMAssay Description:Inhibition of human thymidine phosphorylase by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human thymidine phosphorylase by continuous spectrophotometric assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Tested for inhibitory concentration expressed as displacement of [125I]-labeled substance P from the cloned human Tachykinin receptor 1 expressed in ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.530nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.960nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair