Report error Found 347 with Last Name = 'borroni' and Initial = 'e'
Affinity DataKi: 0.110nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 2C receptor expressed in 3T3 cells using [3H]5-HT as radioligandChecked by AuthorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 83nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 213nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 252nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 368nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 559nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 567nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.12E+3nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 1D receptor expressed in HEK 293 cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 1.44E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.45E+3nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 2A receptor expressed in 3T3 cells using [3H]5-HT as radioligandChecked by AuthorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 1.77E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 2.84E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 2C receptor expressed in 3T3 cells using [3H]5-HT as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 7 receptor expressed in CHO cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 7 receptor expressed in CHO cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 7 receptor expressed in CHO cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 1D receptor expressed in HEK 293 cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 2A receptor expressed in 3T3 cells using [3H]5-HT as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 1D receptor expressed in HEK 293 cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 2C receptor expressed in 3T3 cells using [3H]5-HT as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+5nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 7 receptor expressed in CHO cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+5nMAssay Description:Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 1D receptor expressed in HEK 293 cells using [3H]LSD as radioligandChecked by AuthorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMT: 37°CAssay Description:The binding affinity of the inhibitors towards Catechol O-methyltransferase in the presence of Mg2+ ions were determined by using a radiochemical ass...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMT: 37°CAssay Description:The binding affinity of the inhibitors towards Catechol O-methyltransferase in the presence of Mg2+ ions were determined by using a radiochemical ass...More data for this Ligand-Target Pair