Affinity DataKi: 10nMAssay Description:Binding affinity at Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Affinity DataKi: 13nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Affinity DataKi: 110nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Binding affinity at Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
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Affinity DataKi: 470nMAssay Description:Binding affinity at Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Binding affinity at Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
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Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Binding affinity at Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Binding affinity at Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 7.80E+3nMAssay Description:Non-competitive inhibition of human recombinant-Sialin expressed in HEK293 cells assessed as reduction in [3H]Neu5Ac uptake incubated for 15 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 1.02E+4nMAssay Description:Non-competitive inhibition of human recombinant-Sialin expressed in HEK293 cells assessed as reduction in [3H]Neu5Ac uptake incubated for 15 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of human recombinant-Sialin expressed in HEK293 cells assessed as reduction in [3H]Neu5Ac uptake at 30 to 300 uM incubated for 15 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Binding affinity for mGluR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.40E+4nMAssay Description:Binding affinity for mGluR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.40E+4nMAssay Description:Binding affinity for mGluR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.50E+4nMAssay Description:Binding affinity for mGluR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
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Affinity DataKi: 1.12E+5nMAssay Description:Binding affinity at Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Affinity DataKi: 1.13E+5nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Affinity DataKi: 1.29E+5nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
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Curated by ChEMBL
Affinity DataKi: 8.38E+5nMAssay Description:Binding affinity at Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity for mGluR4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity at Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibitory activity of the compound against human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibitory activity of the compound against human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+3nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant-Sialin expressed in HEK293 cells assessed as reduction in [3H]Neu5Ac uptake at 30 to 300 uM incubated for 15 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity of the compound against human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of VACHT in rat synaptic vesicles assessed as [3H]HT uptake pretreated for 30 mins measured after 10 mins by scintillation spectrophotomet...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 2 in the rat HEK 293 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of human recombinant-Sialin expressed in HEK293 cells assessed as reduction in [3H]Neu5Ac uptake at 30 to 300 uM incubated for 15 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 1 in the rat LLC-PK1/HEK 293 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 1 in the rat LLC-PK1/HEK 293 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 2 in the rat HEK 293 cells.More data for this Ligand-Target Pair