Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 0.378nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 0.396nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nM IC50: 5.70nMpH: 6.0Assay Description:200 μl in 96-well plate. Cell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3H]PGE2 in the absence ...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nM IC50: 10nMpH: 6.0Assay Description:200 μl in 96-well plate. Cell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3H]PGE2 in the absence ...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 74nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 75nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
Affinity DataKi: 258nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 329nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair