Report error Found 167 with Last Name = 'beutler' and Initial = 'ja'
TargetProtein kinase C alpha/beta/gamma/delta/epsilon/eta/theta type/Serine/threonine-protein kinase D1/D3(Human)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Displacement of [3H]PDBu binding to Protein kinase C of CEM cells with 10% fetal calf serumMore data for this Ligand-Target Pair
TargetProtein kinase C alpha/beta/gamma/delta/epsilon/eta/theta type/Serine/threonine-protein kinase D1/D3(Human)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Displacement of [3H]PDBu from Protein kinase C of CEM cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after 1 h...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]-Win55212-2 from human CB1 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]PDBu from rat brain membrane PKCMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of TPA-induced AP1 transfected in HEK293 cells assessed as inhibition of beta-lactamase reporter activity treated 1 hr before TPA stimulat...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of TPA-induced AP1 transfected in HEK293 cells assessed as inhibition of beta-lactamase reporter activity treated 1 hr before TPA stimulat...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]-Win55212-2 from human CB1 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of TPA-induced AP1 transfected in HEK293 cells assessed as inhibition of beta-lactamase reporter activity treated 1 hr before TPA stimulat...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]-Win55212-2 from human CB1 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 131nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 184nMAssay Description:Displacement of [3H]-Win55212-2 from human CB1 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after 1 h...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after 1 h...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 2)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of RNase H activity of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human immunodeficiency virus-1 reverse transcriptase associated RNase H activity using using 18-nucleotide 3,-fluorescein-labeled RNA s...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of HIV1 recombinant integrase by electrochemiluminescent-based high-throughput strand transfer assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of HIV1 reverse transcriptase-associated ribonuclease H activity by fluorescence assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of HIV1 reverse transcriptase-associated ribonuclease H activity by fluorescence assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 664nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells preincubated for 1 hr followed by radioligand addition measured after 1 h...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Stabilization of Pdcd4 expressed in human HEK293 cells assessed as inhibition of TPA-induced degradation by luciferase reporter assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair