Affinity DataKi: 0.0200nM ΔG°: -61.1kJ/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
Affinity DataKi: 0.0320nM ΔG°: -59.9kJ/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nM ΔG°: -58.8kJ/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing rat histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from rat cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:In vitro binding affinity for rat histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]-N-alpha methyl histamine from human H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nM ΔG°: -55.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nM ΔG°: -55.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]-N-alpha methyl histamine from human H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair