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Found 30 with Last Name = 'gazzarrini' and Initial = 's'
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM66082((2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methy...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50433811(CHEMBL2382332)
Affinity DataKi:  11nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50405066(CHEMBL268088)
Affinity DataKi:  70nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50090054(1-(3-Chloro-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,...)
Affinity DataKi:  100nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50090069(1-(3,4-Dichloro-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  110nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50291793(6,6-Dimethyl-1-(3-trifluoromethyl-phenyl)-1,6-dihy...)
Affinity DataKi:  130nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM18792(1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-...)
Affinity DataKi:  410nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataKi:  470nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50267663(CHEMBL4105317)
Affinity DataKi:  1.32E+4nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM18792(1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-...)
Affinity DataKi:  4.30E+4nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis carinii)
Universit£

Curated by ChEMBL
LigandPNGBDBM18792(1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-...)
Affinity DataKi:  1.09E+5nMAssay Description:Inhibition of Pneumocystis carinii DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Universit£

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataKi:  2.80E+5nMAssay Description:Inhibition of Pneumocystis carinii DHFRMore data for this Ligand-Target Pair
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50080000(CHEMBL3415952)
Affinity DataIC50:  800nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266584(CHEMBL4074389)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079994(CHEMBL3305169)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079996(CHEMBL3415948)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079995(CHEMBL3415947)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079999(CHEMBL3415951)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079997(CHEMBL3415949)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266582(CHEMBL4104405)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266585(CHEMBL4096027)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079998(CHEMBL3415950)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266586(CHEMBL4061974)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079996(CHEMBL3415948)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 V27A mutant channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079994(CHEMBL3305169)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 V27A mutant channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079997(CHEMBL3415949)
Affinity DataIC50:  3.22E+4nMAssay Description:Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 V27A mutant channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50343549(3-Azahexacyclo[7.6.0.0(1,5).0(5,12).0(6,10).0(11,1...)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of influenza A virus wild type M2 proton channel expressed in Xenopus oocytes by two-electrode voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266583(CHEMBL4094873)
Affinity DataIC50:  4.53E+4nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2 [1-96](Influenza A virus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079995(CHEMBL3415947)
Affinity DataIC50:  1.85E+5nMAssay Description:Inhibition of Influenza A virus (A/udorn/1972(H3N2)) M2 V27A mutant channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrod...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed