BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Histamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL

BDBM50222968(Cipralisant | GT-2331)

Ki: 0.126nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Histamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL

BDBM50472544(Iodoproxyfan)

Ki: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Histamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL

BDBM50472544(Iodoproxyfan)

Ki: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Histamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL

BDBM50472544(Iodoproxyfan)

Ki: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Histamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL

BDBM50472544(Iodoproxyfan)

Ki: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

G-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

BDBM50189549(CHEMBL3827756)

Ki: 0.219nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair

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Reverse transcriptase protein(Human immunodeficiency virus 1)
Merck

Curated by ChEMBL

BDBM50479471(CHEMBL491019 | MK-1107)

Ki: 0.220nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair

PC cid PC sid PDB

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM18778(CHEMBL22405 | P16 | methyl 4-[2,6-diamino-5-(4-chl...)

Ki: 0.300nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138952(1-(3-Chloro-phenyl)-6-heptyl-1,6-dihydro-[1,3,5]tr...)

Ki: 0.300nMAssay Description:Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparumMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM18790(6-hexyl-5-phenylpyrimidine-2,4-diamine | CHEMBL416...)

Ki: 0.300nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

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PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138945(1-(3-Chloro-phenyl)-6-(4-phenoxy-phenyl)-1,6-dihyd...)

Ki: 0.300nMAssay Description:Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparumMore data for this Ligand-Target Pair

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)

Ki: 0.300nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assayMore data for this Ligand-Target Pair

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Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM50484029(CHEMBL1801258)

Ki: 0.300nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM50484039(CHEMBL1800087)

Ki: 0.300nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

G-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

BDBM50511034(CHEMBL4444010)

Ki: 0.317nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

G-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

BDBM50189527(CHEMBL3827310)

Ki: 0.324nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair

Reverse transcriptase protein(Human immunodeficiency virus 1)
Merck

Curated by ChEMBL

BDBM50479470(CHEMBL489586 | MK-4965)

Ki: 0.390nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair

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Reverse transcriptase protein(Human immunodeficiency virus 1)
Merck

Curated by ChEMBL

BDBM50479470(CHEMBL489586 | MK-4965)

Ki: 0.390nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair

PC cid PC sid PDB

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Histamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL

BDBM50472543(CHEMBL278276)

Ki: 0.398nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Histamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL

BDBM50472543(CHEMBL278276)

Ki: 0.398nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM50484030(CHEMBL1801256)

Ki: 0.400nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)

Ki: 0.400nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL

BDBM50600964(CHEMBL5181335)

Ki: 0.400nMAssay Description:Displacement of [3H]-WIN55212-2 from human CB2 receptor transfected in CHO cells membrane incubated for 90 minsMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details PubMed

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138962(1-(4-Chloro-phenyl)-6-(4-phenoxy-phenyl)-1,6-dihyd...)

Ki: 0.400nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM18779(6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...)

Ki: 0.400nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents Similars

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM18790(6-hexyl-5-phenylpyrimidine-2,4-diamine | CHEMBL416...)

Ki: 0.400nMAssay Description:Binding affinity towards mutant dihydrofolate reductase (N51I+C59R+S108N DHFR) of Plasmodium falciparumMore data for this Ligand-Target Pair

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PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM18787(5-(3-chlorophenyl)-6-[2-(3-phenoxypropoxy)ethyl]py...)

Ki: 0.400nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

CHEMBL PC cid PC sid PDB

Reverse transcriptase protein(Human immunodeficiency virus 1)
Merck

Curated by ChEMBL

BDBM50484635(CHEMBL1939500)

Ki: 0.430nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair

Reverse transcriptase protein(Human immunodeficiency virus 1)
Merck

Curated by ChEMBL

BDBM50484496(CHEMBL1928648)

Ki: 0.480nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair

Reverse transcriptase protein(Human immunodeficiency virus 1)
Merck

Curated by ChEMBL

BDBM50484030(CHEMBL1801256)

Ki: 0.5nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138951(1-(3-Chloro-phenyl)-6-(4-propoxy-phenyl)-1,6-dihyd...)

Ki: 0.5nMAssay Description:Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparumMore data for this Ligand-Target Pair

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM50484045(CHEMBL1801257)

Ki: 0.5nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM50484045(CHEMBL1801257)

Ki: 0.5nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assayMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138965(1-(4-Chloro-phenyl)-6-(3-phenoxy-phenyl)-1,6-dihyd...)

Ki: 0.5nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50110767(4-[2,6-Diamino-5-(3-chloro-phenyl)-pyrimidin-4-yl]...)

Ki: 0.5nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM18791(5-phenyl-6-(3-phenylpropyl)pyrimidine-2,4-diamine ...)

Ki: 0.5nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

Reverse transcriptase protein(Human immunodeficiency virus 1)
Merck

Curated by ChEMBL

BDBM50484632(Mk-6186 | Mk6186)

Ki: 0.580nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

G-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

BDBM50089889(6-(4-Phenyl-butylamino)-1H-pyrimidine-2,4-dione | ...)

Ki: 0.580nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

G-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

BDBM50511014(CHEMBL4547165)

Ki: 0.582nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50110759(4-(2,6-Diamino-5-phenyl-pyrimidin-4-yl)-butyric ac...)

Ki: 0.600nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138946(1-(3-Chloro-phenyl)-6-[3-(3-trifluoromethyl-phenox...)

Ki: 0.600nMAssay Description:Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparumMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138953(1-(4-Chloro-phenyl)-6-hexyl-6-methyl-1,6-dihydro-[...)

Ki: 0.600nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL

BDBM50600966(CHEMBL5205138)

Ki: 0.600nMAssay Description:Inhibition of human CB2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details PubMed

Cannabinoid receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf (Hzdr)

Curated by ChEMBL

BDBM50600961(CHEMBL5198892)

Ki: 0.600nMAssay Description:Displacement of [3H]-SR141716A from recombinant human CB1 receptor expressed in CHO cells membrane incubated for 90 minsMore data for this Ligand-Target Pair

Details PubMed

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM50484030(CHEMBL1801256)

Ki: 0.600nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assayMore data for this Ligand-Target Pair

Reverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory

Curated by ChEMBL

BDBM50484029(CHEMBL1801258)

Ki: 0.600nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assayMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM50138961(1-(3-Chloro-phenyl)-6-[3-(3,5-dichloro-phenoxy)-ph...)

Ki: 0.600nMAssay Description:Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparumMore data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Bifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering And Biotechnology At Thailand

Curated by ChEMBL

BDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)

Ki: 0.600nMAssay Description:Binding affinity towards wild-type dihydrofolate reductase of Plasmodium falciparum.More data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

G-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

BDBM50189502(CHEMBL3827832)

Ki: 0.626nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

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