Found 286 with Last Name = 'badia' and Initial = 'r' TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Binding affinity to wild type HIV-1 p66/p51 reverse transcriptase/nucleic acid/dTTP ternary complex using poly(rA)/oligo(dT) as templates in presence...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Binding affinity to free form of wild type HIV-1 p66/p51 reverse transcriptase using poly(rA)/oligo(dT) as templates in presence of [3H]dTTPMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Binding affinity to wild type HIV-1 p66/p51 reverse transcriptase/nucleic acid binary complex using poly(rA)/oligo(dT) as templates in presence of [3...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed-type inhibition of equine serum BChE using varying levels of butyrylthiocholine iodide as substrate by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed-type inhibition of equine serum BuChE using varying levels of butyrylthiocholine iodide as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 6 mi...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of recombinant HIV-1 p66/p51 reverse transcriptase K103N mutant assessed as inhibition of [3H]dTT...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus-infected insect cells using Rh-EVNLDAEFK-quencher as substrate mea...More data for this Ligand-Target Pair
3D Structure (crystal)TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase Y181I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of recombinant HIV-1 p66/p51 reverse transcriptase K103N mutant assessed as inhibition of [3H]dTT...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase V106A mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase V106A mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of wild type recombinant HIV-1 His-tagged p66/p51 reverse transcriptase assessed as inhibition of...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 NL4-3 reverse transcriptase His-tagged p66/p51 associated RNA dependent DNA polymerase activity expressed in Escherichia coli asse...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of recombinant HIV-1 p66/p51 reverse transcriptase K103N mutant assessed as inhibition of [3H]dTT...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of wild type recombinant HIV-1 His-tagged p66/p51 reverse transcriptase assessed as inhibition of...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza Universit£
Curated by ChEMBL
Sapienza Universit£
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of recombinant HIV-1 p66/p51 reverse transcriptase K103N mutant assessed as inhibition of [3H]dTT...More data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 15 mins measured after 8 mins in presence or absence of ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of Torpedo californica AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase V106A mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase V106A mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activityMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
