Found 33 with Last Name = 'beardsley' and Initial = 'gp' TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 60nM ΔG°: -41.4kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetPhosphoribosylglycinamide formyltransferase(Escherichia coli (strain K12))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 100nM ΔG°: -40.1kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 130nM ΔG°: -38.9kJ/molepH: 7.4 T: 2°CAssay Description:The human ATIC enzyme was used for the inhibition assay using the spectrophotometric method monitoring the appearance of IMP by measuring absorbance ...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 150nM ΔG°: -38.6kJ/molepH: 7.4 T: 2°CAssay Description:The human ATIC enzyme was used for the inhibition assay using the spectrophotometric method monitoring the appearance of IMP by measuring absorbance ...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 230nM ΔG°: -37.5kJ/molepH: 7.4 T: 2°CAssay Description:The human ATIC enzyme was used for the inhibition assay using the spectrophotometric method monitoring the appearance of IMP by measuring absorbance ...More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 4.80E+3nM ΔG°: -30.5kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetPhosphoribosylglycinamide formyltransferase(Escherichia coli (strain K12))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.9kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.9kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.9kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetPhosphoribosylglycinamide formyltransferase(Escherichia coli (strain K12))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.9kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetPhosphoribosylglycinamide formyltransferase(Escherichia coli (strain K12))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.9kJ/molepH: 7.5 T: 2°CAssay Description:Assays were initiated by the addition of GAR to the reaction mixture containing GAR Tfase, test compounds, and cofactor. The assay monitors the defor...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.5 T: 2°CAssay Description:Recombinant human AICAR Tfase was used in the inhibition assay. The reaction was monitored at 298 nm by measuring the increase in absorbance correspo...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.5 T: 2°CAssay Description:Recombinant human AICAR Tfase was used in the inhibition assay. The reaction was monitored at 298 nm by measuring the increase in absorbance correspo...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.5 T: 2°CAssay Description:Recombinant human AICAR Tfase was used in the inhibition assay. The reaction was monitored at 298 nm by measuring the increase in absorbance correspo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory concentration against beef liver dihydrofolate reductaseMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 3.30nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:In vitro inhibitory concentration against beef liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:In vitro inhibitory concentration against beef liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated in vitro for its ability to inhibit the Dihydrofolate reductase extracted from beef liver.More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+4nMAssay Description:In vitro inhibitory concentration against beef liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+4nMAssay Description:In vitro inhibitory concentration against Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20E+4nMAssay Description:In vitro inhibitory concentration against Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+5nMAssay Description:In vitro inhibitory concentration against Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+5nMAssay Description:In vitro inhibitory concentration against beef liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20E+5nMAssay Description:In vitro inhibitory concentration against Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
