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Found 22 with Last Name = 'bekhit' and Initial = 'ael-d'
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  260nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: <300nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: <300nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM50292563(4-(4-{[3-(4-Chloro-phenyl)-4-oxo-thiazolidin-2-yli...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50:  780nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50:  920nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM50292564(CHEMBL476870 | N-[1-Dimethylamino-methylidene]-4-(...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50:  1.26E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM50292562(4-(4-{[4-(4-Bromo-phenyl)-3-p-tolyl-3H-thiazol-2-y...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50:  1.35E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.63E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50:  7.64E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50:  8.36E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM50292564(CHEMBL476870 | N-[1-Dimethylamino-methylidene]-4-(...)
Affinity DataIC50:  8.71E+4nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50:  9.42E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM50292562(4-(4-{[4-(4-Bromo-phenyl)-3-p-tolyl-3H-thiazol-2-y...)
Affinity DataIC50:  9.62E+4nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM50292563(4-(4-{[3-(4-Chloro-phenyl)-4-oxo-thiazolidin-2-yli...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed