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Found 102 with Last Name = 'burgin' and Initial = 'ab'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049413(CHEMBL3313945 | US11401286, Example 52)
Affinity DataIC50:  7nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049407(CHEMBL3315271 | US11401286, Example 51)
Affinity DataIC50:  12nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049407(CHEMBL3315271 | US11401286, Example 51)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049410(CHEMBL3315265 | US11401286, Example 41)
Affinity DataIC50:  20nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50073854(2,10-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of topoisomerase I-DNA complex in trapping assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049410(CHEMBL3315265 | US11401286, Example 41)
Affinity DataIC50:  46nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50008935((20S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of topoisomerase I-DNA complex in trapping assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50346121(2-(4-(2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpy...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human PDE4B1More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049416(CHEMBL3315273)
Affinity DataIC50:  63nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
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LigandPNGBDBM50294161((R)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)pyrro...)
Affinity DataIC50:  69nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049416(CHEMBL3315273)
Affinity DataIC50:  69nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50294161((R)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)pyrro...)
Affinity DataIC50:  71nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50294162((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...)
Affinity DataIC50:  81nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049418(CHEMBL3315275 | US11401286, Example 59)
Affinity DataIC50:  96nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049417(CHEMBL3315272)
Affinity DataIC50:  126nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049417(CHEMBL3315272)
Affinity DataIC50:  132nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049415(CHEMBL3315267 | US11401286, Example 49)
Affinity DataIC50:  135nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049411(CHEMBL3315266 | US11401286, Example 38)
Affinity DataIC50:  135nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50294163((R)-N-benzyl-4-(pyrrolidin-2-ylmethoxy)aniline | C...)
Affinity DataIC50:  157nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049412(CHEMBL3315274)
Affinity DataIC50:  160nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049413(CHEMBL3313945 | US11401286, Example 52)
Affinity DataIC50:  165nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50294162((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...)
Affinity DataIC50:  189nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50294163((R)-N-benzyl-4-(pyrrolidin-2-ylmethoxy)aniline | C...)
Affinity DataIC50:  207nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049253(CHEMBL3315262 | US11401286, Example 28)
Affinity DataIC50:  207nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049408(CHEMBL3315270 | US11401286, Example 40)
Affinity DataIC50:  213nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049406(CHEMBL3315263 | US11401286, Example 29)
Affinity DataIC50:  219nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049406(CHEMBL3315263 | US11401286, Example 29)
Affinity DataIC50:  220nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049146(CHEMBL3315251 | US11401286, Example 36)
Affinity DataIC50:  237nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049408(CHEMBL3315270 | US11401286, Example 40)
Affinity DataIC50:  241nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049211(CHEMBL3315261 | US11401286, Example 30)
Affinity DataIC50:  251nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049102(CHEMBL3315250 | US11401286, Example 34)
Affinity DataIC50:  251nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049211(CHEMBL3315261 | US11401286, Example 30)
Affinity DataIC50:  261nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049415(CHEMBL3315267 | US11401286, Example 49)
Affinity DataIC50:  268nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049411(CHEMBL3315266 | US11401286, Example 38)
Affinity DataIC50:  268nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of topoisomerase I-DNA complex in trapping assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049070(CHEMBL3315248 | US11401286, Example 27)
Affinity DataIC50:  383nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049412(CHEMBL3315274)
Affinity DataIC50:  402nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049419(CHEMBL3315276 | US11401286, Example 60)
Affinity DataIC50:  600nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049409(CHEMBL3315269 | US11401286, Example 39)
Affinity DataIC50:  681nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049153(CHEMBL3315258)
Affinity DataIC50:  726nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049150(CHEMBL3315255)
Affinity DataIC50:  727nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049409(CHEMBL3315269 | US11401286, Example 39)
Affinity DataIC50:  781nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049153(CHEMBL3315258)
Affinity DataIC50:  845nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049152(CHEMBL3315257)
Affinity DataIC50:  859nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049070(CHEMBL3315248 | US11401286, Example 27)
Affinity DataIC50:  865nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049414(CHEMBL3315264 | US11401286, Example 26)
Affinity DataIC50:  886nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049418(CHEMBL3315275 | US11401286, Example 59)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049146(CHEMBL3315251 | US11401286, Example 36)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049068(CHEMBL3315246 | US11401286, Example 22)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049253(CHEMBL3315262 | US11401286, Example 28)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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