Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human cloned muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M1 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]N-methyl scopalamine from human cloned muscarinic M3 receptor expressed in CHO cells coexpressing Gqi5 by scintillation proximity...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]-N-methyl scopolamine from muscarinic acetylcholine M2 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-N-methyl scopolamine from muscarinic acetylcholine M1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]N-methyl scopalamine from human cloned muscarinic M3 receptor expressed in CHO cells coexpressing Gqi5 by scintillation proximity...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]N-methyl scopalamine from human cloned muscarinic M2 receptor expressed in CHO cells coexpressing Gqi5 by scintillation proximity...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]-N-methyl scopolamine from muscarinic acetylcholine M3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]N-methyl scopalamine from human cloned muscarinic M1 receptor expressed in CHO cells coexpressing Gqi5 by scintillation proximity...More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M2 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic acetylcholine M1 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M1 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Displacement of [3H]N-methyl scopalamine from human cloned muscarinic M1 receptor expressed in CHO cells coexpressing Gqi5 by scintillation proximity...More data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M2 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Displacement of [3H]N-methyl scopalamine from human cloned muscarinic M2 receptor expressed in CHO cells coexpressing Gqi5 by scintillation proximity...More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic acetylcholine M2 receptor expressed in CHO cells coexpressed with Gqi5 by scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic acetylcholine M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competition of [3H]rolipram binding sites in the central nervous system (HPDE4) in rat brain cytosolMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competition of [3H]rolipram binding sites in the central nervous system (HPDE4) in rat brain cytosolMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Concentration required to inhibit [125I]IL-8 binding towards C-X-C chemokine receptor type 2 of human expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Concentration required to inhibit [125I]IL-8 binding towards C-X-C chemokine receptor type 2 of human expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity against human M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Concentration required to inhibit [125I]IL-8 binding towards C-X-C chemokine receptor type 2 of human expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at human muscarinic acetylcholine M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobi...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair