Affinity DataIC50: 0.0700nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant FAAH expressed in Cos7 cells after 30 mins by using anandamide as a substrate by LC-MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant MAGL expressed in Cos7 cells after 30 mins by using 2-AG as a substrate by LC-MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of MAGL in C57B1/6J mouse brain membrane after 30 mins by using 2-AG as a substrate by LC-MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of MAGL-mediated [14C]1-oleoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of FAAH in C57B1/6J mouse brain membrane after 20 mins by using oleamide as a substrate by LC-MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptor expressed in HEK293 cells in presence of mouse brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MAGL in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Agonist activity at CB1 receptor in mouse brain membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKd: 0.860nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in mouse brain at 100 nMMore data for this Ligand-Target Pair