Compile Data Set for Download or QSAR
maximum 50k data
Found 53 with Last Name = 'christie' and Initial = 'ph'
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)
Affinity DataKi:  0.00280nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50405400(CHEMBL2051987)
Affinity DataKi:  0.00300nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50405400(CHEMBL2051987)
Affinity DataKi:  0.00300nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50010932((10-DA, 10-Deazaminopterin)2-{4-[2-(2,4-Diamino-pt...)
Affinity DataKi:  0.00340nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50226274(CHEMBL3349020)
Affinity DataKi:  0.00400nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00400nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataKi:  0.00520nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014706(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-butyl]-benzoyl...)
Affinity DataKi:  0.00550nMAssay Description:Concentration of the compound inhibiting Dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells.More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00600nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50008287(2-{4-[2-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-yl)-...)
Affinity DataKi:  0.00700nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50008287(2-{4-[2-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-yl)-...)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50405401(CHEMBL2051990)
Affinity DataKi:  0.0120nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50008285(2-{4-[1-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylme...)
Affinity DataKi:  0.0130nMAssay Description:Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50008285(2-{4-[1-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylme...)
Affinity DataKi:  0.0130nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50008286(2-[4-(1,3-Diamino-7,8,9,10-tetrahydro-pyrimido[4,5...)
Affinity DataKi:  0.0170nMAssay Description:Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)
Affinity DataKi:  990nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50024475(2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-quinazo...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014935(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014936(2-{4-[1-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50010932((10-DA, 10-Deazaminopterin)2-{4-[2-(2,4-Diamino-pt...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibitory activity of the compound towards Dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014706(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-butyl]-benzoyl...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibitory activity of the compound towards Dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  10nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226274(CHEMBL3349020)
Affinity DataIC50:  14nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  19nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50226274(CHEMBL3349020)
Affinity DataIC50:  19nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50004544(2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405399(CHEMBL2051989)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405399(CHEMBL2051989)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50004544(2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-...)
Affinity DataIC50:  22nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405401(CHEMBL2051990)
Affinity DataIC50:  22nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50025007(2-{4-[2-(2,4-Diamino-7,8-dihydro-pteridin-6-yl)-et...)
Affinity DataIC50:  32nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50025008(2-{4-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pteridin-6...)
Affinity DataIC50:  34nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50025007(2-{4-[2-(2,4-Diamino-7,8-dihydro-pteridin-6-yl)-et...)
Affinity DataIC50:  34nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50405399(CHEMBL2051989)
Affinity DataIC50:  35nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50405399(CHEMBL2051989)
Affinity DataIC50:  35nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50405401(CHEMBL2051990)
Affinity DataIC50:  38nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405398(CHEMBL2051991)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50025008(2-{4-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pteridin-6...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405398(CHEMBL2051991)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50014706(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-butyl]-benzoyl...)
Affinity DataIC50:  70nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50405398(CHEMBL2051991)
Affinity DataIC50:  120nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50405398(CHEMBL2051991)
Affinity DataIC50:  120nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Sri International

Curated by ChEMBL
LigandPNGBDBM50014707(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-propyl]-benzoy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration of the compound inhibiting AICAR formyltransferase enzyme of L. caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Sri International

Curated by ChEMBL
LigandPNGBDBM50014706(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-butyl]-benzoyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration of the compound inhibiting AICAR formyltransferase enzyme of L. caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 53 total ) | Next | Last >>
Jump to: