Affinity DataIC50: 0.300nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
TargetCysteine proteinase falcipain 3(Plasmodium falciparum)
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of Cysteine protease falcipain-3 in Plasmodium falciparum HB3 infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis assayMore data for this Ligand-Target Pair
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of Cysteine protease falcipain-2 in Plasmodium falciparum HB3 infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis assayMore data for this Ligand-Target Pair
TargetCysteine proteinase falcipain 3(Plasmodium falciparum)
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of Cysteine protease falcipain-3 in Plasmodium falciparum HB3-leuR1 mutant infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis ass...More data for this Ligand-Target Pair
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
National Institute Of Allergy And Infectious Diseases
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of Cysteine protease falcipain-2 in Plasmodium falciparum HB3-leuR1 mutant infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis ass...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human UGT1A1 using bilirubin as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant UGT1A1 using bilirubin as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant UGT1A1 using bilirubin as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human UGT1A1 using bilirubin as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of midazolam as substrate preincubated for 30 mins in presence of NADPH follo...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of testosterone as substrate preincubated for 30 mins in presence of NADPH fo...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of UGT1A1 in rat liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant rat UGT1A1 using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP3A4 using vivid green as substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human ERG by patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant rat UGT1A1 using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of CYP3A4 using vivid red as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of midazolam as substrate preincubated for 30 mins in presence of NADPH follo...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of UGT1A1 in rat liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of testosterone as substrate preincubated for 30 mins in presence of NADPH fo...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of testosterone as substrate preincubated for 0 mins in presence of NADPH fol...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of midazolam as substrate preincubated for 0 mins in presence of NADPH follow...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of midazolam as substrate preincubated for 0 mins in presence of NADPH follow...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Bristol Myers Squibb Research And Early Development
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP3A4 in human pooled liver microsomes in presence of testosterone as substrate preincubated for 0 mins in presence of NADPH fol...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair