Affinity DataKi: 0.0100nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to human Prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Ligand InfoPDB
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Binding affinity to Escherichia coli K12 Prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Ligand InfoPDB
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate...More data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Binding affinity to human Prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 232nMAssay Description:Binding affinity to ADK (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 280nMAssay Description:Binding affinity to Escherichia coli K12 glutaminyl-tRNA synthetase assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 490nMAssay Description:Binding affinity to Escherichia coli K12 Prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 690nMAssay Description:Binding affinity to human HGPRT assessed as inhibition of constantMore data for this Ligand-Target Pair
Ligand Info
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Johns Hopkins University
Curated by ChEMBL
Johns Hopkins University
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Uncompetitive inhibition of human kidney glutaminase (124 to 669) assessed as reduction of glutamine hydrolysis by double-reciprocal plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:Competitive inhibition of pig kidney DAAO using D-Alanine as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminally tagged human recombinant GCP2 (44 to 750 residues) extracellular domain expressed in Drosophila melanogaster S2 cells prei...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of N-terminally tagged human recombinant GCP2 (44 to 750 residues) extracellular domain expressed in Drosophila melanogaster S2 cells prei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 1.93nMAssay Description:Displacement of [3H]WIN35,428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 3.26nMAssay Description:Displacement of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of N-terminally tagged human recombinant GCP2 (44 to 750 residues) extracellular domain expressed in Drosophila melanogaster S2 cells prei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of MraY in Escherichia coliMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 12nMAssay Description:Antimicrobial activity against Enterococcus faecalis ATCC 29212 assessed as microbial growth inhibitionMore data for this Ligand-Target Pair
Ligand Info
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Escherichia coli K12 methionyl tRNA synthetaseMore data for this Ligand-Target Pair
Ligand Info
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminally tagged human recombinant GCP2 (44 to 750 residues) extracellular domain expressed in Drosophila melanogaster S2 cells prei...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Staphylococcus aureus MraYMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 17nMAssay Description:Inhibition of N-terminally tagged human recombinant GCP2 (44 to 750 residues) extracellular domain expressed in Drosophila melanogaster S2 cells prei...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of Bacillus subtilis MraYMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 22nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assayMore data for this Ligand-Target Pair