Compile Data Set for Download or QSAR
maximum 50k data
Found 100 with Last Name = 'forino' and Initial = 'm'
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8443(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataKi:  32nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8435(3-[(5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylide...)
Affinity DataKi:  800nM IC50:  1.70E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Burnham Institute

LigandPNGBDBM15186(4-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cy...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.0kJ/mole IC50:  2.60E+3nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  2.70E+3nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Burnham Institute

LigandPNGBDBM15187(3-[(2E)-3-(1H-1,3-benzodiazol-2-yl)prop-2-enoyl]-6...)
Affinity DataKi:  3.90E+3nM ΔG°:  -30.9kJ/mole IC50:  4.50E+3nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  4.30E+3nM ΔG°:  -30.3kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  6.20E+3nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Burnham Institute

LigandPNGBDBM15188(5-{5-[(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)me...)
Affinity DataKi:  2.08E+4nM ΔG°:  -26.7kJ/mole IC50:  2.51E+4nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10216(BI-7E7 | Burnham Institute Compound 2 | ethyl 2-(2...)
Affinity DataKi:  3.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8442(2-[(5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methy...)
Affinity DataIC50:  265nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8441(2-[(5Z)-5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl...)
Affinity DataIC50:  298nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8439(2-[(5Z)-5-{[5-(4-chloro-2-nitrophenyl)furan-2-yl]m...)
Affinity DataIC50:  500nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8444(2-[(5Z)-4-oxo-5-[(5-phenylthiophen-2-yl)methyliden...)
Affinity DataIC50:  740nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8438(2-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  850nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8437(2-[(5Z)-5-{[5-(4-chlorophenyl)furan-2-yl]methylide...)
Affinity DataIC50:  900nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8458(5-[(5-phenylthiophen-2-yl)methylidene]-2-sulfanyli...)
Affinity DataIC50:  1.20E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8456(5-({5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-...)
Affinity DataIC50:  1.30E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8447(2-[(5Z)-5-[(5-{[(5Z)-3-(carboxymethyl)-4-oxo-2-sul...)
Affinity DataIC50:  1.60E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50384998(CVD-0019905 | XANTHOHUMOL)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8457(5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylidene}-...)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8434(4-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  2.30E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8459(2-[(5Z)-4-oxo-2-sulfanylidene-5-{[5-(thiophen-2-yl...)
Affinity DataIC50:  2.30E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8432(3-[(5Z)-5-{[5-(4-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  2.70E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8433(2-chloro-4-(5-{[(5Z)-4-oxo-3-(prop-2-en-1-yl)-2-su...)
Affinity DataIC50:  2.70E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8431(4-(5-{[(5Z)-4-oxo-2-sulfanylidene-3-[3-(trifluorom...)
Affinity DataIC50:  2.90E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50384998(CVD-0019905 | XANTHOHUMOL)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8464(5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl]methyli...)
Affinity DataIC50:  3.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8440(2-[(5Z)-5-{[5-(2-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  3.10E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8430(2-[(5Z)-5-{[5-(3-nitrophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  3.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8446(2-[(5Z)-5-{[5-(4-chlorophenyl)thiophen-2-yl]methyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8460(5-{[5-(4-chlorophenyl)furan-2-yl]methylidene}-2-su...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8451(2-[(5Z)-5-{[5-(4-bromophenyl)-1,3-thiazol-2-yl]met...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8429(4-(5-{[(5Z)-3-(4-nitrophenyl)-4-oxo-2-sulfanyliden...)
Affinity DataIC50:  4.80E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8450(2-[(5Z)-5-{[5-(3,4-dimethoxyphenyl)-1,3-thiazol-2-...)
Affinity DataIC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8428(2-[(5Z)-5-{[5-(4-iodophenyl)furan-2-yl]methylidene...)
Affinity DataIC50:  5.50E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8463(2-[(5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methy...)
Affinity DataIC50:  5.60E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177002(CHEMBL3814590)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8452(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  5.90E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8427(4-(5-{[(5Z)-3-benzyl-4-oxo-2-sulfanylidene-1,3-thi...)
Affinity DataIC50:  6.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8426((5Z)-5-{[5-(4-bromo-3-chlorophenyl)furan-2-yl]meth...)
Affinity DataIC50:  7.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8425((5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylid...)
Affinity DataIC50:  7.40E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8424(2-[(5Z)-4-oxo-5-{[5-(4-sulfamoylphenyl)furan-2-yl]...)
Affinity DataIC50:  9.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177000(CHEMBL3814665)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8423(2-chloro-4-(5-{[(5Z)-4-oxo-3-(pyridin-3-ylmethyl)-...)
Affinity DataIC50:  9.90E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8449(2-[(5Z)-5-{[5-(4-chlorophenyl)-1,3-thiazol-2-yl]me...)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177001(Xanthohumol C)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177000(CHEMBL3814665)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177003(CHEMBL3813911)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM19460((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177002(CHEMBL3814590)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 100 total ) | Next | Last >>
Jump to: