Affinity DataIC50: 0.900nMAssay Description:Inhibition of HDAC3 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HDAC1 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Agonist activity at human GST-tagged estrogen receptor alpha ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Agonist activity at human GST-tagged estrogen receptor beta ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC2 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC6 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Agonist activity at human GST-tagged estrogen receptor beta ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+3nMAssay Description:Agonist activity at human GST-tagged estrogen receptor alpha ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HDAC3 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of HDAC1 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full-length HDAC2 preincubated for 20 mins with DTT followed by enzyme addition and measured after 10 mins by Glo-lum...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC2 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human full-length HDAC2 preincubated for 20 mins with DTT followed by enzyme addition and measured after 10 mins by Glo-lum...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HDAC8 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HDAC6 in human DU-145 cells assessed as increase in histone H3 acetylation after 24 hrs by immunofluorescence microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant human full-length HDAC2 preincubated for 20 mins with DTT followed by enzyme addition and measured after 10 mins by Glo-lum...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human full-length HDAC2 preincubated for 20 mins with DTT followed by enzyme addition and measured after 10 mins by Glo-lum...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant human full-length HDAC2 preincubated for 20 mins with DTT followed by enzyme addition and measured after 10 mins by Glo-lum...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant human full-length HDAC2 preincubated for 20 mins with DTT followed by enzyme addition and measured after 10 mins by Glo-lum...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human full-length HDAC2 incubated for 10 mins by Glo-luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human full-length HDAC2 incubated for 10 mins by Glo-luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of recombinant human full-length HDAC2 incubated for 10 mins by Glo-luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of recombinant human full-length HDAC2 incubated for 10 mins by Glo-luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of recombinant human full-length HDAC2 incubated for 10 mins by Glo-luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of recombinant human full-length HDAC2 incubated for 10 mins by Glo-luminescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.29E+3nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0220nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at estrogen receptor alpha (unknown origin) assessed as inhibition of estradiol-induced response after 22 hrs by cell-based lucif...More data for this Ligand-Target Pair
Affinity DataEC50: 0.310nMAssay Description:Agonist activity at estrogen receptor alpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.52E+3nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+4nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+3nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.151nMAssay Description:Agonist activity at GAL4 DNA binding domain fused full-length chimeric estrogen receptor beta (unknown origin) by FRET-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 357nMAssay Description:Agonist activity at GAL4 DNA binding domain fused full-length chimeric estrogen receptor beta (unknown origin) by FRET-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 930nMAssay Description:Agonist activity at GAL4 DNA binding domain fused full-length chimeric estrogen receptor alpha (unknown origin) by FRET-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 101nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 65nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 75nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at estrogen receptor alpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at estrogen receptor alpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at estrogen receptor alpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair