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Found 90 with Last Name = 'fujino' and Initial = 'y'
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343939((S)-2-(6-hydroxy-6-methylheptan-2-ylamino)-4-methy...)
Affinity DataKi:  0.590nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343938(CHEMBL1778662 | rac-2-(6-hydroxy-6-methylheptan-2-...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  2nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343947(2-(6-hydroxy-6-methylheptylamino)-4-methyl-6-(5-me...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343941(2-(hexylthio)-4-methyl-6-(5-methyl-1H-pyrazol-3-yl...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343945(2-(6-hydroxyhexylamino)-4-methyl-6-(5-methyl-1H-py...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of aurora CMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343937(CHEMBL1780257 | N-(4-(3-cyano-4-methyl-6-(5-methyl...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343942(2-(6-hydroxyhexylthio)-4-methyl-6-(5-methyl-1H-pyr...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343946(2-(6-hydroxy-6-methylheptylthio)-4-methyl-6-(5-met...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  18nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343944(2-(2-hydroxyethylamino)-4-methyl-6-(5-methyl-1H-py...)
Affinity DataKi:  20nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343938(CHEMBL1778662 | rac-2-(6-hydroxy-6-methylheptan-2-...)
Affinity DataKi:  24nMAssay Description:Inhibition of YesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343938(CHEMBL1778662 | rac-2-(6-hydroxy-6-methylheptan-2-...)
Affinity DataKi:  26nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343938(CHEMBL1778662 | rac-2-(6-hydroxy-6-methylheptan-2-...)
Affinity DataKi:  28nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343943(2-(6-aminohexylthio)-4-methyl-6-(5-methyl-1H-pyraz...)
Affinity DataKi:  28nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  30nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343940((R)-2-(6-hydroxy-6-methylheptan-2-ylamino)-4-methy...)
Affinity DataKi:  66nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343938(CHEMBL1778662 | rac-2-(6-hydroxy-6-methylheptan-2-...)
Affinity DataKi:  101nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50343936(CHEMBL1780256 | N-(4-(3-cyano-6-(5-methyl-1H-pyraz...)
Affinity DataKi:  310nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  14nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50277584(CHEMBL482968 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-m...)
Affinity DataIC50:  290nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104486(CHEMBL432562 | [(S)-1-[(S)-1-{12-[(2-Chloro-phenox...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50097316(CHEMBL351995 | Phosphoric acid 12-(2-{1-[2-(5-chlo...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50097324(CHEMBL413033 | Phosphoric acid 3-chloro-phenyl est...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104475(CHEMBL83388 | Phosphoric acid 2-chloro-phenyl este...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104490(CHEMBL314864 | [(R)-1-{12-[(2-Chloro-phenoxy)-hydr...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50097326((2-Chloro-phenyl)-phosphonic acid mono-(11-{2-[1-(...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibitory concentration against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104495((R)-4-tert-Butoxycarbonylamino-4-[(R)-1-{12-[(2-ch...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50097318(CHEMBL155030 | Phosphoric acid 12-(2-{1-[2-(5-chlo...)
Affinity DataIC50:  6.70E+3nMAssay Description:Competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104466(CHEMBL314040 | {(R)-1-[(R)-1-{12-[(2-Chloro-phenox...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104484(CHEMBL314057 | Phosphoric acid 12-[(R)-2-benzoylam...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50097327(CHEMBL345715 | Phosphoric acid 12-(2-{1-[2-(5-chlo...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory concentration against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104473((R)-2-[(R)-1-{12-[(2-Chloro-phenoxy)-hydroxy-phosp...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104489(CHEMBL313020 | Phosphoric acid 12-[(S)-2-[(R)-2-am...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104464(CHEMBL405650 | Phosphoric acid 12-[(S)-2-[(S)-2-am...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104467(CHEMBL437042 | {[(R)-1-{12-[(2-Chloro-phenoxy)-hyd...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104471(CHEMBL87995 | Phosphoric acid 12-[(R)-2-[(R)-2-ami...)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104469(CHEMBL85749 | Phosphoric acid 12-[(S)-2-amino-3-(1...)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104457(CHEMBL85239 | [(R)-1-{12-[(2-Chloro-phenoxy)-hydro...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104470(CHEMBL431613 | [(R)-1-[(R)-1-{12-[(2-Chloro-phenox...)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50097332(12-(2-{1-[3-(3-Methyl-indol-1-yl)-propyl]-1H-indol...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104465(CHEMBL85748 | [(S)-1-{12-[(2-Chloro-phenoxy)-hydro...)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104478(CHEMBL409072 | Phosphoric acid 12-[(R)-2-((R)-2-am...)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104497(CHEMBL87116 | Phosphoric acid 12-[(R)-2-[(R)-2-ace...)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104483(CHEMBL313009 | Phosphoric acid 2-chloro-phenyl est...)
Affinity DataIC50:  2.94E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104499(CHEMBL313818 | Phosphoric acid 2-chloro-phenyl est...)
Affinity DataIC50:  2.97E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50097320(12-{2-[1-(3-Phenoxy-propyl)-1H-indol-3-yl]-acetyla...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibitory concentration against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50104485(CHEMBL86349 | Phosphoric acid 2-chloro-phenyl este...)
Affinity DataIC50:  3.39E+4nMAssay Description:Inhibitory activity against telomerase extracted from HCT 116 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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