Compile Data Set for Download or QSAR
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Found 199 with Last Name = 'gordon' and Initial = 'rj'
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036480(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.00800nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036476(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036478(3-Carboxymethoxy-2,6-dichloro-benzoic acid 4-isopr...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036477(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036481(2,6-Dichloro-3-[(2-dimethylamino-ethyl)-methyl-sul...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036475(2,6-Dichloro-3-(2-pyrrolidin-1-yl-ethoxy)-benzoic ...)
Affinity DataKi:  0.0140nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50029699(2,6-Dichloro-benzoic acid 4-isopropyl-6-methoxy-1,...)
Affinity DataKi:  0.0230nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50039631(2,6-Dichloro-benzoic acid 4-isopropyl-1,1,3-trioxo...)
Affinity DataKi:  0.0300nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286326(2,6-Dichloro-benzoic acid 6-fluoro-4-isopropyl-1,1...)
Affinity DataKi:  0.0300nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034671(CHEMBL41327 | Phosphoric acid diethyl ester 4-isop...)
Affinity DataKi:  0.0350nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034676(CHEMBL41881 | Phosphoric acid 4-sec-butyl-1,1,3-tr...)
Affinity DataKi:  0.0700nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034677(CHEMBL288810 | Phosphoric acid diethyl ester 4-iso...)
Affinity DataKi:  0.100nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036482(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.200nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286333(5,6-Dimethoxy-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-...)
Affinity DataKi:  0.200nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50029703(4-Isopropyl-6-methoxy-1,1-dioxo-2-(1-phenyl-1H-tet...)
Affinity DataKi:  0.270nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50282874(4-Isopropyl-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-yl...)
Affinity DataKi:  0.300nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50282873(4-sec-Butyl-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-yl...)
Affinity DataKi:  0.600nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286327(4,6-Dimethoxy-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-...)
Affinity DataKi:  0.600nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50282868(1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...)
Affinity DataKi:  0.700nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286329(2,6-Dichloro-benzoic acid 4-isopropyl-6-(4-methyl-...)
Affinity DataKi:  1.10nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50282866(4-Ethyl-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulf...)
Affinity DataKi:  2nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286330(4,5-Dimethoxy-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-...)
Affinity DataKi:  2nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286328(2,6-Dichloro-benzoic acid 6-dimethylamino-4-isopro...)
Affinity DataKi:  2.20nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034668(CHEMBL39165 | Phosphoric acid diethyl ester 6-hydr...)
Affinity DataKi:  4.5nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286332(4-Isopropyl-5,6-dimethoxy-1,1-dioxo-2-(1-phenyl-1H...)
Affinity DataKi:  5.20nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034678(CHEMBL288700 | Phosphoric acid diphenyl ester 1,1,...)
Affinity DataKi:  6.5nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50282878(4-Methoxy-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-ylsu...)
Affinity DataKi:  14nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50286331(4,7-Dimethoxy-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-...)
Affinity DataKi:  15nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036479(1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...)
Affinity DataKi:  15nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036479(1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...)
Affinity DataKi:  15nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034674(CHEMBL291271 | Phosphoric acid dibutyl ester 1,1,3...)
Affinity DataKi:  17nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034672(CHEMBL290748 | Phosphoric acid dibenzyl ester 1,1,...)
Affinity DataKi:  20.5nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034675(CHEMBL41874 | Dibutyl-phosphinic acid 1,1,3-trioxo...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034670(CHEMBL38479 | Diphenyl-phosphinic acid 1,1,3-triox...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034673(CHEMBL41423 | Phosphoric acid diethyl ester 1,1,3-...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034673(CHEMBL41423 | Phosphoric acid diethyl ester 1,1,3-...)
Affinity DataKi:  60nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKi:  60nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006819(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-phenethyl-aceta...)
Affinity DataKi:  100nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase in human cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50034669(CHEMBL290189 | Phosphoric acid dimethyl ester 1,1,...)
Affinity DataKi:  100nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataKi:  800nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataKi:  1.00E+3nMAssay Description:Activity of the compound to bind against [3H]-LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006819(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-phenethyl-aceta...)
Affinity DataKi:  1.60E+3nMAssay Description:In vitro inhibitory activity against rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50282867(4-tert-Butyl-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-y...)
Affinity DataKi: >2.00E+3nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataKi:  1.00E+5nMAssay Description:Activity of the compound to bind against [3H]-LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016671(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-(1-phenyl-ethyl...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016680(5-Phenyl-pentanoic acid benzyl-hydroxy-amide | CHE...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016694(4-Benzyloxy-N-hydroxy-N-phenethyl-benzamide | CHEM...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50009932(4-Ethylsulfanyl-1-phenyl-pyrazolidin-3-one | CHEMB...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of rat 5-LipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016679(CHEMBL52085 | N-Hydroxy-N-methyl-2-[3-(quinolin-2-...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006819(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-phenethyl-aceta...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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