Affinity DataKi: 1.25E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells assessed as inhibitory constant incubated fo...More data for this Ligand-Target Pair
Affinity DataKi: 1.93E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells assessed as inhibitory constant incubated fo...More data for this Ligand-Target Pair
Affinity DataKi: 9.27E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells assessed as inhibitory constant incubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibition of recombinant wild type human N-terminal His6-tagged BTK expressed in baculovirus incubated for 20 mins by TR-FRET based competitive bind...More data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of His-tagged human recombinant soluble epoxide hydrolase pre-incubated for 15 mins before Epoxy-fluor7 substrate addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of His-tagged human recombinant soluble epoxide hydrolase pre-incubated for 15 mins before Epoxy-fluor7 substrate addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK C481S mutant expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of His6/TEV fused-GST-tagged Flt3 (unknown origin) (H564 to S993 residues) using Axltide (CKKSRGDYMTMQJ-acid) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of His-tagged human ERalpha pre-incubated for 15 mins before fluorescent ligand addition and measured after 1 hr by fluorescence polarizat...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant c-Kit (unknown origin) incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged Tyro3 (unknown origin) (453 to 890 residues) using Axltide (KKSRGDYMTMQIG-acid) peptide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of His6/TEV fused-GST-tagged Flt3 (unknown origin) (H564 to S993 residues) using Axltide (CKKSRGDYMTMQJ-acid) peptide as substrate preincu...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of His-tagged human ERalpha pre-incubated for 15 mins before fluorescent ligand addition and measured after 1 hr by fluorescence polarizat...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Google Research Applied Science, Mountain View, California 94043, United States.
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant c-Kit (unknown origin) incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of GST-tagged Tyro3 (unknown origin) (453 to 890 residues) using Axltide (KKSRGDYMTMQIG-acid) peptide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK C481S mutant expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of His6/TEV fused-GST-tagged Flt3 (unknown origin) (H564 to S993 residues) using Axltide (CKKSRGDYMTMQJ-acid) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of GST-tagged Tyro3 (unknown origin) (453 to 890 residues) using Axltide (KKSRGDYMTMQIG-acid) peptide as substrate preincubated for 30 min...More data for this Ligand-Target Pair