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Found 55 with Last Name = 'hodnick' and Initial = 'wf'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188136((3aS,8R,8aS)-6,7-dichloro-8-methyl-1,2,3,3a,8,8a-h...)
Affinity DataKi:  5nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188139((3aS,8R,8aS)-6-chloro-5-methoxy-8-methyl-1,2,3,3a,...)
Affinity DataKi:  14nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188144((3aS,8R,8aS)-6-bromo-5-methoxy-8-methyl-1,2,3,3a,8...)
Affinity DataKi:  27nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188140((3aS,8R,8aS)-6-chloro-8-methyl-1,2,3,3a,8,8a-hexah...)
Affinity DataKi:  27nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188143((+/-)-(3aS,8aS)-5,6-dichloro-8-methyl-1,2,3,3a,8,8...)
Affinity DataKi:  103nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188134((+/-)-(3aS,8aS)-6-chloro-5,8-dimethyl-1,2,3,3a,8,8...)
Affinity DataKi:  107nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188127((3aS,8R,8aS)-5-chloro-6,8-dimethyl-1,2,3,3a,8,8a-h...)
Affinity DataKi:  134nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188129((3aS,8R,8aS)-5,6-dichloro-8-methyl-1,2,3,3a,8,8a-h...)
Affinity DataKi:  155nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188137((3aS,8R,8aS)-6-chloro-5,8-dimethyl-1,2,3,3a,8,8a-h...)
Affinity DataKi:  155nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188142((+/-)-(3aS,8aS)-5-bromo-6,8-dimethyl-1,2,3,3a,8,8a...)
Affinity DataKi:  207nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188146((3aS,8R,8aS)-6-chloro-5-ethoxy-8-methyl-1,2,3,3a,8...)
Affinity DataKi:  231nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188130((+/-)-(3aS,8aS)-6-bromo-5,8-dimethyl-1,2,3,3a,8,8a...)
Affinity DataKi:  463nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188128((+/-)-(3aS,8aS)-5-chloro-6,8-dimethyl-1,2,3,3a,8,8...)
Affinity DataKi:  465nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188135((+/-)-(3aS,8aS)-6-chloro-5-methoxy-8-methyl-1,2,3,...)
Affinity DataKi:  530nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188125((3aS,8R,8aS)-6-chloro-8-methyl-1,2,3,3a,8,8a-hexah...)
Affinity DataKi:  911nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188132((3aS,8S,8aS)-5,6-dichloro-8-methyl-1,2,3,3a,8,8a-h...)
Affinity DataKi:  1.14E+3nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188147((+/-)-(3aS,8aS)-6,8-dimethyl-1,2,3,3a,8,8a-hexahyd...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188141((+/-)-(3aS,8aS)-4,8-dimethyl-1,2,3,3a,8,8a-hexahyd...)
Affinity DataKi:  1.85E+3nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188131((+/-)-(3aS,8aS)-5-fluoro-8-methyl-1,2,3,3a,8,8a-he...)
Affinity DataKi:  3.01E+3nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188138((+/-)-(3aS,8aS)-5,8-dimethyl-1,2,3,3a,8,8a-hexahyd...)
Affinity DataKi:  3.31E+3nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188133((+/-)-(3aS,8aS)-7,8-dimethyl-1,2,3,3a,8,8a-hexahyd...)
Affinity DataKi:  3.38E+3nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188145((+/-)-(3aS,8aS)-6-fluoro-8-methyl-1,2,3,3a,8,8a-he...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  57nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184585((3aS,6aS)-1-(3-chlorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  503nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184597((3aS,6aS)-5-(4-(2,5-dichlorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >2.00E+4nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  40nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  22nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184593((3aS,6aS)-5-(4-(2,5-difluorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >2.00E+4nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184590((3aS,6aS)-1-(3-fluorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  108nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188125((3aS,8R,8aS)-6-chloro-8-methyl-1,2,3,3a,8,8a-hexah...)
Affinity DataEC50:  54nMAssay Description:Inhibition of 5HT2C assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188126((3aS,8aS)-6-chloro-1,2,3,3a,8,8a-hexahydro-indeno[...)
Affinity DataEC50:  11nMAssay Description:Inhibition of 5HT2C assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50188139((3aS,8R,8aS)-6-chloro-5-methoxy-8-methyl-1,2,3,3a,...)
Affinity DataEC50:  6nMAssay Description:Inhibition of 5HT2C assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184592((3aS,6aS)-1-(3-(trifluoromethyl)phenyl)-octahydrop...)
Affinity DataEC50:  168nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  23nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  116nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184596((2S,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  151nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184594((3aS,6aS)-5-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50: >2.00E+4nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184595((3aR,6aR)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  519nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184585((3aS,6aS)-1-(3-chlorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  416nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184592((3aS,6aS)-1-(3-(trifluoromethyl)phenyl)-octahydrop...)
Affinity DataEC50:  103nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184590((3aS,6aS)-1-(3-fluorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  1.12E+3nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184587((2R,3aS,6aS)-2-methyl-1-(4-(trifluoromethyl)pyrimi...)
Affinity DataEC50:  48nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(CHEMBL208936 | rac-1-(4-(trifluoromethyl)pyrimidin...)
Affinity DataEC50:  180nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184592((3aS,6aS)-1-(3-(trifluoromethyl)phenyl)-octahydrop...)
Affinity DataEC50:  65nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184588((3aS,4S,6aR)-4-(3-(trifluoromethyl)phenyl)-octahyd...)
Affinity DataEC50:  187nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184588((3aS,4S,6aR)-4-(3-(trifluoromethyl)phenyl)-octahyd...)
Affinity DataEC50:  1.08E+3nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(CHEMBL208936 | rac-1-(4-(trifluoromethyl)pyrimidin...)
Affinity DataEC50:  220nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184591((3aS,6aS)-1-(4-(2,5-difluorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184590((3aS,6aS)-1-(3-fluorophenyl)-octahydropyrrolo[3,4-...)
Affinity DataEC50:  319nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50184589((3aS,6aS)-1-(4-(2,5-dichlorophenyl)pyrimidin-2-yl)...)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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