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Found 145 with Last Name = 'huch' and Initial = 'v'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataKi:  3nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409039(CHEMBL2111951)
Affinity DataKi:  3nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataKi:  6nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409039(CHEMBL2111951)
Affinity DataKi:  7nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataKi:  8nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataKi:  9nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093602(17-(1H-Imidazol-4-yl)-10,13-dimethyl-2,3,4,7,8,9,1...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114564(CHEMBL3608378)
Affinity DataIC50:  80nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50006551((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094190(10,13-Dimethyl-17-(2H-pyrazol-3-yl)-2,3,4,7,8,9,10...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114565(CHEMBL3608855)
Affinity DataIC50:  180nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50:  210nMAssay Description:Inhibition of Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114427(CHEMBL3608361)
Affinity DataIC50:  220nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114425(CHEMBL3608359)
Affinity DataIC50:  240nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114426(CHEMBL3608360)
Affinity DataIC50:  290nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409039(CHEMBL2111951)
Affinity DataIC50:  290nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114428(Myrtucommulone H)
Affinity DataIC50:  300nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114563(CHEMBL3608377)
Affinity DataIC50:  300nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114430(CHEMBL3608363)
Affinity DataIC50:  390nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  400nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409040(CHEMBL2111948)
Affinity DataIC50:  420nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409039(CHEMBL2111951)
Affinity DataIC50:  430nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114420(CHEMBL3608858)
Affinity DataIC50:  430nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114425(CHEMBL3608359)
Affinity DataIC50:  460nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114420(CHEMBL3608858)
Affinity DataIC50:  460nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114422(CHEMBL3608860)
Affinity DataIC50:  480nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114551(CHEMBL3608367)
Affinity DataIC50:  490nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  530nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409041(CHEMBL2111947)
Affinity DataIC50:  540nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114560(CHEMBL3608374)
Affinity DataIC50:  570nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114567(Myrtucommulone F)
Affinity DataIC50:  600nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114552(CHEMBL3608368)
Affinity DataIC50:  610nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114431(CHEMBL3608364)
Affinity DataIC50:  640nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114421(CHEMBL3608859)
Affinity DataIC50:  650nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114427(CHEMBL3608361)
Affinity DataIC50:  660nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114566(CHEMBL3608856)
Affinity DataIC50:  680nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114554(CHEMBL3608370)
Affinity DataIC50:  680nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114420(CHEMBL3608858)
Affinity DataIC50:  690nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114419(CHEMBL3608857)
Affinity DataIC50:  730nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  740nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114562(CHEMBL3608376)
Affinity DataIC50:  810nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114419(CHEMBL3608857)
Affinity DataIC50:  810nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114429(CHEMBL3608362)
Affinity DataIC50:  820nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114426(CHEMBL3608360)
Affinity DataIC50:  970nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409046(CHEMBL2112782)
Affinity DataIC50:  970nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114551(CHEMBL3608367)
Affinity DataIC50:  980nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114423(MYRTUCOMMULONE A)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114556(CHEMBL3608372)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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