Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]NMS from human M2R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Displacement of [3H]NMS from human M2R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]NMS from human M3R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]NMS from human M2R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]NMS from human M3R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]NMS from human M3R expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic substrate S2302 by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic substrate S2302 by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human thrombin using chromogenic substrate S2238 by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human thrombin using chromogenic substrate S2238 by dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 12.8nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research
Curated by ChEMBL
Institute For Bio-Medical Research
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 18.3nMAssay Description:A BB2 receptor binding test was carried out using a membrane sample prepared from a human prostate cancer-derived PC-3 cell. The PC-3 cell was cultur...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 28.6nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair