TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 112nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 186nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 214nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 217nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 266nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 268nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 341nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 429nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 450nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 457nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 468nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 595nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 602nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 610nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 705nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 778nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.55E+3nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.57E+3nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.69E+3nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.98E+3nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.57E+3nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5.70E+3nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.90E+3nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity for 5-HT3 receptor of NG108-15 cells using [3H]-GR-65,630More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human HuTu80 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair